Personalized Binuclear Enzyme Inhibition Platform

Publication ID: 24-11857657_0010_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Personalized Binuclear Enzyme Inhibition Platform,” Published Technical Disclosure No. 24-11857657_0010_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857657_0010_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,657.

Summary of the Inventive Concept

A next-generation platform for treating diseases and conditions mediated by binuclear enzymes, leveraging AI-driven molecular design, personalized skin analysis, and transdermal delivery to provide customized and effective treatments.

Background and Problem Solved

The original patent disclosed diarylalkane compounds as potent inhibitors of binuclear enzymes, but it had limitations in terms of compound synthesis, skin penetration, and personalized treatment. The new inventive concept addresses these limitations by introducing AI-driven molecular design, personalized skin analysis, and transdermal delivery, enabling more effective and targeted treatments.

Detailed Description of the Inventive Concept

The platform comprises a database of diarylalkane compounds, a skin analysis module, and a recommendation engine that selects a customized diarylalkane composition based on an individual's skin type, condition, and desired outcome. The AI-driven molecular design system predicts optimal molecular structures for inhibiting binuclear enzymes and generates novel compounds for further testing and development. The transdermal delivery system ensures sustained and targeted delivery of the active ingredient. The novel class of diarylalkane compounds having modified general structures enhances bioavailability, stability, or skin penetration.

Novelty and Inventive Step

The new claims introduce AI-driven molecular design, personalized skin analysis, and transdermal delivery, which are not present in the original patent. The combination of these elements provides a novel and non-obvious solution for treating diseases and conditions mediated by binuclear enzymes.

Alternative Embodiments and Variations

Alternative embodiments may include the use of other AI algorithms, different transdermal delivery systems, or additional skin analysis parameters. Variations may include the application of this platform to other diseases and conditions beyond skin pigmentation, such as cancer or neurodegenerative diseases.

Potential Commercial Applications and Market

The personalized binuclear enzyme inhibition platform has significant commercial potential in the cosmetics and pharmaceutical industries, particularly in the areas of skin care and dermatology. The platform's ability to provide customized and effective treatments could disrupt the existing market and create new opportunities for companies and researchers.

CPC Classifications

SectionClassGroup
A A61 A61K8/347
A A61 A61K8/31
A A61 A61K8/4973
A A61 A61K8/9789
A A61 A61K8/9794
A A61 A61K31/015
A A61 A61K31/05
A A61 A61K31/085
A A61 A61K31/09
A A61 A61K31/357
A A61 A61K31/40
A A61 A61K31/704
A A61 A61Q19/02
C C07 C07C39/15
C C07 C07C39/367
C C07 C07C41/26
C C07 C07C41/32
C C07 C07C43/23
C C07 C07C45/673
C C07 C07C49/835
C C07 C07C215/74
C C07 C07D321/12
A A61 A61K2800/782
Y Y02 Y02A50/30

Original Patent Information

Patent NumberUS 11,857,657
TitleDiarylalkanes as potent inhibitors of binuclear enzymes
Assignee(s)Unigen, Inc.