Silk-based Solutions for Diverse Industries

Publication ID: 24-11857663_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Silk-based Solutions for Diverse Industries,” Published Technical Disclosure No. 24-11857663_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857663_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,663.

Summary of the Inventive Concept

This inventive concept leverages the core technology of stable silk protein fragment compositions to address pressing needs in various industries, including agriculture, packaging, medical devices, and water purification.

Background and Problem Solved

The original patent disclosed stable silk protein fragment compositions, primarily focused on medical applications. However, these compositions have untapped potential in other fields. This inventive concept solves the problem of limited scope by applying the core technology to new, high-impact use cases.

Detailed Description of the Inventive Concept

The inventive concept comprises four main applications: (1) agricultural pest control, where silk protein fragments prevent pest infestation; (2) plant growth enhancement, using silk protein fragment-based fertilizers; (3) biodegradable packaging materials, formed from silk protein fragment matrices; and (4) medical implant coatings and water purification membranes, both utilizing silk protein fragments to enhance biocompatibility and selectively filter contaminants.

Novelty and Inventive Step

The new claims introduce entirely novel applications of the stable silk protein fragment compositions, departing from the original medical focus. The inventive step lies in recognizing the potential of these compositions to address distinct problems in diverse industries.

Alternative Embodiments and Variations

Alternative embodiments may include using silk protein fragments in cosmetics, textiles, or 3D printing. Variations could involve combining silk protein fragments with other biomaterials or adjusting their molecular weights to tailor their properties for specific applications.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential, targeting industries such as agriculture, packaging, medical devices, and water purification. The market size for these applications is substantial, with potential for high revenue growth and social impact.

CPC Classifications

SectionClassGroup
A A61 A61K8/64
A A45 A45D33/00
A A61 A61K8/02
A A61 A61K8/0216
A A61 A61K8/042
A A61 A61K8/19
A A61 A61K8/27
A A61 A61K8/29
A A61 A61K8/365
A A61 A61K8/4953
A A61 A61K8/676
A A61 A61K8/735
A A61 A61K8/922
A A61 A61K8/97
A A61 A61K8/9789
A A61 A61K8/9794
A A61 A61K8/987
A A61 A61K9/08
A A61 A61K31/375
A A61 A61K38/00
A A61 A61K38/012
A A61 A61K45/06
A A61 A61K47/02
A A61 A61K47/12
A A61 A61K47/36
A A61 A61Q17/04
A A61 A61Q19/00
A A61 A61Q19/007
A A61 A61Q19/02
A A61 A61Q19/08
C C07 C07K1/12
C C07 C07K14/43586
A A61 A61K2800/591
A A61 A61K2800/72
A A61 A61K2800/74
A A61 A61K2800/75

Field of Art

Biomaterials and protein engineering, with expertise in silk protein processing, material science, and interdisciplinary applications spanning medical, agricultural, and industrial domains

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degrees in materials science, bioengineering, or chemical engineering, possessing knowledge of protein modification techniques, material characterization, and cross-industry biomaterial applications

Obviousness Rationale

A PHOSITA would recognize that the stable silk protein fragment compositions disclosed in US 11857663 inherently possess versatile properties enabling broad technological applications. The molecular characteristics of these fragments - specifically their controlled molecular weight and stability - make them naturally adaptable to diverse industrial contexts. Given silk proteins' known biocompatibility and functional versatility, extending their use to agricultural, packaging, and filtration applications represents a predictable engineering progression.

Obvious Combinations & Variations

Source Patent Element
Lyophilized silk fibroin protein fragments with controlled molecular weight range (17-45 kDa)
PTD Variation
Agricultural pest control composition using silk protein fragments
Obviousness Reasoning
A PHOSITA would recognize that protein fragments with defined molecular characteristics could be easily adapted for surface interactions, making pest control a predictable application of known protein engineering principles
Source Patent Element
Stable, non-gelating silk protein fragment solutions
PTD Variation
Biodegradable packaging materials formed from silk protein fragment matrices
Obviousness Reasoning
The inherent stability and processability of the silk protein fragments naturally suggest their utility in forming consistent, uniform material structures suitable for packaging applications
Source Patent Element
Silk fibroin protein fragments with minimal sericin content
PTD Variation
Medical implant coatings enhancing biocompatibility
Obviousness Reasoning
The purified protein fragments' inherent biocompatibility and controllable molecular properties make them an obvious choice for developing medical surface modifications
Source Patent Element
Reconstitutable silk protein fragment solutions in water
PTD Variation
Water purification membranes using selective filtration properties
Obviousness Reasoning
A PHOSITA would recognize that protein fragments with defined molecular weights and solution behaviors could be engineered into selective membrane structures through standard materials science techniques
Source Patent Element
Silk protein fragments with controlled molecular characteristics
PTD Variation
Plant growth enhancement fertilizer compositions
Obviousness Reasoning
The protein fragments' potential for surface interactions and nutrient delivery make their adaptation to agricultural enhancement a predictable engineering solution
35 U.S.C. § 103 Summary: Based on the teachings of US 11857663 and the disclosed variations, a person of ordinary skill in the art would find the extension of stable silk protein fragment compositions into agricultural, packaging, medical, and filtration applications to be obvious and predictable. The molecular engineering principles underlying the source patent inherently suggest these diverse technological implementations, rendering subsequent claims covering such applications unpatentable under standard obviousness analysis.

Original Patent Information

Patent NumberUS 11,857,663
TitleStable silk protein fragment compositions
Assignee(s)EVOLVED BY NATURE, INC.