Intelligent Silk-Based Systems for Biomedical and Cosmetic Applications

Publication ID: 24-11857663_0003_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Intelligent Silk-Based Systems for Biomedical and Cosmetic Applications,” Published Technical Disclosure No. 24-11857663_0003_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857663_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,663.

Summary of the Inventive Concept

This inventive concept integrates silk protein fragment compositions with advanced technologies such as AI, IoT, blockchain, and nanomaterials to create innovative systems for biomedical and cosmetic applications.

Background and Problem Solved

The original patent disclosed stable silk protein fragment compositions with controlled molecular weights. However, these compositions lacked the ability to interact with modern technologies, limiting their potential in real-world applications. The new inventive concept addresses this limitation by combining the silk protein fragment compositions with AI, IoT, blockchain, and nanomaterials to create powerful systems for personalized medicine, customized cosmetic products, wearable devices, implantable devices, and real-time monitoring.

Detailed Description of the Inventive Concept

The inventive concept comprises a silk protein fragment composition with a controlled molecular weight, integrated with one or more advanced technologies. For example, a silk-based biomedical system may incorporate an AI-powered diagnostic module for personalized medicine, while a silk-based cosmetic system may utilize a blockchain-secured supply chain for authentication and tracking. The silk protein fragment composition can be fabricated into various forms, such as films, gels, or powders, and can be integrated with IoT-enabled communication modules, nanomaterial-based delivery systems, or spectroscopy-based detection modules.

Novelty and Inventive Step

The new inventive concept is novel and non-obvious in its integration of silk protein fragment compositions with advanced technologies, enabling new functionalities and applications that were not possible with the original patent. The inventive step lies in the unexpected combination of these technologies, which results in synergistic effects and improved performance.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept may include the use of different types of silk protein fragments, varying molecular weights and polydispersities, or alternative advanced technologies such as robotics or augmented reality. Variations may also include different fabrication methods, such as 3D printing or electrospinning, or the incorporation of additional components, such as sensors or actuators.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the biomedical and cosmetic industries, with applications in personalized medicine, customized cosmetic products, wearable devices, implantable devices, and real-time monitoring. The market for these applications is growing rapidly, driven by increasing demand for innovative, high-performance materials and systems.

CPC Classifications

SectionClassGroup
A A61 A61K8/64
A A45 A45D33/00
A A61 A61K8/02
A A61 A61K8/0216
A A61 A61K8/042
A A61 A61K8/19
A A61 A61K8/27
A A61 A61K8/29
A A61 A61K8/365
A A61 A61K8/4953
A A61 A61K8/676
A A61 A61K8/735
A A61 A61K8/922
A A61 A61K8/97
A A61 A61K8/9789
A A61 A61K8/9794
A A61 A61K8/987
A A61 A61K9/08
A A61 A61K31/375
A A61 A61K38/00
A A61 A61K38/012
A A61 A61K45/06
A A61 A61K47/02
A A61 A61K47/12
A A61 A61K47/36
A A61 A61Q17/04
A A61 A61Q19/00
A A61 A61Q19/007
A A61 A61Q19/02
A A61 A61Q19/08
C C07 C07K1/12
C C07 C07K14/43586
A A61 A61K2800/591
A A61 A61K2800/72
A A61 A61K2800/74
A A61 A61K2800/75

Original Patent Information

Patent NumberUS 11,857,663
TitleStable silk protein fragment compositions
Assignee(s)EVOLVED BY NATURE, INC.