Silk-based Environmental Remediation and Sustainability Systems

Publication ID: 24-11857664_0007_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Silk-based Environmental Remediation and Sustainability Systems,” Published Technical Disclosure No. 24-11857664_0007_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857664_0007_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,664.

Summary of the Inventive Concept

This inventive concept leverages the unique properties of silk fibroin protein fragments to develop novel systems for environmental remediation, sustainable agriculture, water filtration, bioremediation of oil spills, and sustainable construction materials.

Background and Problem Solved

The original patent disclosed stable silk protein fragment compositions, primarily focused on medical applications. However, the environmental and sustainability sectors face significant challenges, including pollution, climate change, and resource depletion. This inventive concept addresses these limitations by applying the core technology to new, impactful areas.

Detailed Description of the Inventive Concept

The inventive concept encompasses a range of systems and methods that utilize silk fibroin protein fragments with specific average weight average molecular weights to tackle various environmental and sustainability challenges. For instance, compositions with molecular weights ranging from 6 kDa to 16 kDa can absorb and break down pollutants in contaminated soil and water, while those with molecular weights between 17 kDa and 38 kDa can promote healthy microbial growth and increase crop yields in sustainable agricultural systems. Other embodiments include membranes for water filtration, bioremediation systems for oil spills, and sustainable construction materials.

Novelty and Inventive Step

The new claims introduce novel applications and use cases for silk fibroin protein fragments, departing from the original patent's medical focus. The inventive step lies in recognizing the potential of these protein fragments to address pressing environmental and sustainability challenges, and in developing specific compositions and systems tailored to these new applications.

Alternative Embodiments and Variations

Alternative embodiments could include silk-based systems for air purification, biodegradable packaging materials, or even biomedical applications in non-human animals. Variations of the inventive concept could involve combining silk fibroin protein fragments with other biopolymers or materials to enhance their performance and versatility.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in various industries, including environmental remediation, sustainable agriculture, water treatment, construction materials, and biotechnology. The market for these applications is substantial, with growing demand for eco-friendly and sustainable solutions.

CPC Classifications

SectionClassGroup
A A61 A61K8/64
A A45 A45D33/00
A A61 A61K8/02
A A61 A61K8/0216
A A61 A61K8/042
A A61 A61K8/19
A A61 A61K8/27
A A61 A61K8/29
A A61 A61K8/365
A A61 A61K8/4953
A A61 A61K8/676
A A61 A61K8/735
A A61 A61K8/922
A A61 A61K8/97
A A61 A61K8/9789
A A61 A61K8/9794
A A61 A61K8/987
A A61 A61K9/08
A A61 A61K31/375
A A61 A61K38/00
A A61 A61K38/012
A A61 A61K45/06
A A61 A61K47/02
A A61 A61K47/12
A A61 A61K47/36
A A61 A61Q17/04
A A61 A61Q19/00
A A61 A61Q19/007
A A61 A61Q19/02
A A61 A61Q19/08
C C07 C07K1/12
C C07 C07K14/43586
A A61 A61K2800/591
A A61 A61K2800/72
A A61 A61K2800/74
A A61 A61K2800/75

Field of Art

Biomaterials engineering, with a focus on protein-based materials, environmental remediation technologies, and sustainable material applications. Requires advanced degree in materials science, bioengineering, or chemical engineering with expertise in protein modification, material characterization, and applied materials development

Person of Ordinary Skill (PHOSITA) Profile

A skilled practitioner with knowledge of protein engineering, material science principles, and interdisciplinary applications of biomaterials. Capable of understanding molecular weight variations, protein structural modifications, and translating laboratory protein research into practical technological solutions

Obviousness Rationale

The PTD represents a predictable extension of the source patent's silk fibroin protein fragment teachings by applying known molecular weight ranges to novel environmental applications. A PHOSITA would recognize that the inherent properties of silk fibroin protein fragments - such as absorption capacity, structural flexibility, and biocompatibility - naturally suggest potential uses beyond medical applications. The systematic exploration of molecular weight ranges for different environmental technologies represents a logical and incremental innovation consistent with standard materials engineering practices.

Obvious Combinations & Variations

Source Patent Element
Silk fibroin protein fragments with 17 kDa to 38 kDa molecular weight
PTD Variation
Using these fragments for sustainable agricultural microbial growth promotion
Obviousness Reasoning
Predictable application of known protein material properties to agricultural enhancement, representing a standard design choice in biomaterials engineering
Source Patent Element
Composition with crystalline and amorphous protein domains
PTD Variation
Creating water filtration membranes leveraging protein structural characteristics
Obviousness Reasoning
Known protein engineering technique of utilizing inherent material properties for separation and filtration technologies
Source Patent Element
Substantially solid silk fibroin protein fragment compositions
PTD Variation
Developing environmental remediation systems for pollutant absorption
Obviousness Reasoning
Obvious extension of material properties, applying known protein absorption mechanisms to environmental challenges
Source Patent Element
Silk protein fragments devoid of sericin
PTD Variation
Creating sustainable construction materials with enhanced structural properties
Obviousness Reasoning
Predictable materials engineering approach of leveraging purified protein fragments for structural applications
Source Patent Element
Protein fragments with defined molecular weight ranges
PTD Variation
Bioremediation systems for oil spill cleanup
Obviousness Reasoning
Logical application of known protein material absorption and breakdown capabilities to environmental remediation challenges
35 U.S.C. § 103 Summary: Based on US Patent 11857664's comprehensive disclosure of silk fibroin protein fragment compositions, the present publication demonstrates that the claimed environmental and sustainability applications would have been obvious to a person having ordinary skill in biomaterials engineering. The systematic exploration of molecular weight ranges and protein fragment characteristics represents a predictable variation within the established technological framework, thereby rendering subsequent claims of novelty invalid under standard obviousness analysis.

Original Patent Information

Patent NumberUS 11,857,664
TitleStable silk protein fragment compositions
Assignee(s)EVOLVED BY NATURE, INC.