Silk Protein Fragment Compositions for Specialized Applications
Legal Citation
Summary of the Inventive Concept
The present inventive concept relates to silk protein fragment compositions tailored for specific, narrow markets or unique operational environments, such as disaster relief, high-security needs, extreme weather conditions, and biodegradable packaging materials.
Background and Problem Solved
The original patent disclosed stable silk protein fragment compositions with varying crystalline protein domains and molecular weights. However, these compositions were not specifically designed for specialized applications, limiting their potential in addressing unique challenges. The present inventive concept addresses this limitation by adapting the silk protein fragment compositions for specific, high-value markets.
Detailed Description of the Inventive Concept
The inventive concept comprises silk protein fragments with tailored molecular weights and crystalline protein domains for distinct applications. For disaster relief, fragments with molecular weights ranging from about 6 kDa to about 16 kDa are used. For high-security biometric identification, fragments with molecular weights ranging from about 17 kDa to about 38 kDa are employed. In extreme weather conditions, fragments with polydispersity ranging from about 1.5 to about 3.0 are utilized. For high-temperature environments, fragments with molecular weights ranging from about 35 kDa to about 40 kDa are used. Lastly, for biodegradable packaging materials, fragments with molecular weights ranging from about 40 kDa to about 50 kDa are incorporated into a biodegradable matrix.
Novelty and Inventive Step
The present inventive concept's novelty lies in the adaptation of silk protein fragment compositions for specific, narrow markets or unique operational environments, which is non-obvious compared to the original patent. The inventive step involves the deliberate design of silk protein fragments with tailored properties to address the unique challenges of these specialized applications.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include silk protein fragment compositions for other specialized applications, such as medical implants, aerospace materials, or sustainable textiles. Variations could involve combining silk protein fragments with other biomaterials or incorporating them into composite structures.
Potential Commercial Applications and Market
The present inventive concept has significant commercial potential in various industries, including disaster relief, biotechnology, security, and sustainable packaging. The target markets for these specialized silk protein fragment compositions are expected to be high-value and high-growth, driven by the increasing demand for tailored solutions in these areas.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K8/64 |
| A | A45 | A45D33/00 |
| A | A61 | A61K8/02 |
| A | A61 | A61K8/0216 |
| A | A61 | A61K8/042 |
| A | A61 | A61K8/19 |
| A | A61 | A61K8/27 |
| A | A61 | A61K8/29 |
| A | A61 | A61K8/365 |
| A | A61 | A61K8/4953 |
| A | A61 | A61K8/676 |
| A | A61 | A61K8/735 |
| A | A61 | A61K8/922 |
| A | A61 | A61K8/97 |
| A | A61 | A61K8/9789 |
| A | A61 | A61K8/9794 |
| A | A61 | A61K8/987 |
| A | A61 | A61K9/08 |
| A | A61 | A61K31/375 |
| A | A61 | A61K38/00 |
| A | A61 | A61K38/012 |
| A | A61 | A61K45/06 |
| A | A61 | A61K47/02 |
| A | A61 | A61K47/12 |
| A | A61 | A61K47/36 |
| A | A61 | A61Q17/04 |
| A | A61 | A61Q19/00 |
| A | A61 | A61Q19/007 |
| A | A61 | A61Q19/02 |
| A | A61 | A61Q19/08 |
| C | C07 | C07K1/12 |
| C | C07 | C07K14/43586 |
| A | A61 | A61K2800/591 |
| A | A61 | A61K2800/72 |
| A | A61 | A61K2800/74 |
| A | A61 | A61K2800/75 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Biomaterials engineering, specifically protein fragment processing and modification for specialized applications, with expertise in silk protein manipulation, molecular weight characterization, and materials design across medical, packaging, and environmental domains
Person of Ordinary Skill (PHOSITA) Profile
A skilled practitioner with advanced degrees in materials science, bioengineering, or polymer chemistry, possessing knowledge of protein fragment processing techniques, molecular weight fractionation methods, and experience in designing protein-based materials for specific functional requirements
Obviousness Rationale
A person having ordinary skill in the art would recognize that the source patent's comprehensive disclosure of silk fibroin protein fragment compositions provides a foundational framework for targeted molecular weight and crystalline domain modifications. The PTD's specialized applications represent predictable extensions of known silk protein engineering principles, utilizing standard fractionation and molecular weight selection techniques. The variations demonstrate routine optimization of silk protein fragments for specific environmental and functional requirements within the established technological framework.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,664 |
|---|---|
| Title | Stable silk protein fragment compositions |
| Assignee(s) | EVOLVED BY NATURE, INC. |