Synergistic Biotherapeutic Agent Delivery Systems

Publication ID: 24-11857670_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Biotherapeutic Agent Delivery Systems,” Published Technical Disclosure No. 24-11857670_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857670_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,670.

Summary of the Inventive Concept

The invention integrates nanoporous implantable canisters with cutting-edge technologies like AI, IoT, blockchain, and advanced materials to create a new generation of personalized, adaptive, and efficient biotherapeutic agent delivery systems.

Background and Problem Solved

The original patent provided a biocompatible, nanoporous device for delivering cellular and biotherapeutic agents. However, it lacked real-time monitoring, personalized medicine capabilities, and advanced integration with other technologies. The new inventive concept addresses these limitations by combining the patented nanoporous canister with AI, IoT, blockchain, and novel materials to create a more powerful, adaptive, and efficient system.

Detailed Description of the Inventive Concept

The synergistic biotherapeutic agent delivery system comprises a nanoporous canister integrated with an AI-powered sensor for real-time monitoring of agent release, a blockchain-secured, patient-specific biotherapeutic agent, and IoT-enabled monitoring to track agent efficacy. The system can be further enhanced with modular, 3D-printed, nanoscale-patterned surfaces for tissue integration and machine learning algorithms for predicting optimal agent release profiles. The hybrid, implantable canister combines a nanoporous, metallic outer shell with a polymeric, nanoscale-patterned inner surface to enhance agent stability and provide structural support.

Novelty and Inventive Step

The new inventive concept's integration of AI, IoT, blockchain, and advanced materials with the patented nanoporous canister provides a non-obvious and novel solution for personalized, adaptive, and efficient biotherapeutic agent delivery. The inventive step lies in the synergistic combination of these distinct technologies to create a more powerful system.

Alternative Embodiments and Variations

Alternative embodiments may include variations in the AI algorithm, IoT connectivity, blockchain security, and materials used. Additionally, the system could be adapted for different types of biotherapeutic agents, tissues, or diseases, ensuring broad conceptual coverage.

Potential Commercial Applications and Market

The synergistic biotherapeutic agent delivery system has significant commercial potential in the fields of personalized medicine, tissue engineering, and regenerative medicine. The target market includes pharmaceutical companies, medical device manufacturers, and healthcare providers seeking to improve treatment outcomes and patient care.

CPC Classifications

SectionClassGroup
A A61 A61K9/0024
A A61 A61F2/022
A A61 A61K31/337
A A61 A61K31/397
A A61 A61K31/436
A A61 A61K31/65
A A61 A61K31/7036
A A61 A61K35/28
A A61 A61K38/14
A A61 A61K38/1866
A A61 A61K38/22
A A61 A61K39/395
A A61 A61K47/02
A A61 A61M39/0247
A A61 A61M2039/027
A A61 A61M2039/0261
A A61 A61M2039/0276
A A61 A61M2205/04

Original Patent Information

Patent NumberUS 11,857,670
TitleImplantable cellular and biotherapeutic agent delivery canister
Assignee(s)NanoVault Medical LLC