Copper-based Microbiome Modulation for Diverse Health Applications

Publication ID: 24-11857675_0007_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Copper-based Microbiome Modulation for Diverse Health Applications,” Published Technical Disclosure No. 24-11857675_0007_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857675_0007_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,675.

Summary of the Inventive Concept

A novel approach to leveraging copper's antimicrobial properties to develop innovative solutions for various health issues, including respiratory diseases, cognitive function, skin diseases, eye diseases, and athletic performance.

Background and Problem Solved

The original patent disclosed a method for reducing HPV incidence and prevalence by modifying the cervical microbiome. However, this technology has untapped potential for addressing other significant health concerns. The new inventive concept expands on this core technology to tackle unmet needs in diverse fields, providing a comprehensive solution for various diseases and health issues.

Detailed Description of the Inventive Concept

The new inventive concept encompasses a range of copper-based devices and systems designed to modulate the microbiome in different parts of the body. For instance, a respiratory device with a surface area between 100 mm2 to 200 mm2 can be used to reduce the incidence of respiratory diseases by modifying the respiratory microbiome. Similarly, a wearable device with a surface area between 50 mm2 to 100 mm2 can enhance cognitive function by increasing local immunity in the brain. Other embodiments include skin patches, eye masks, and athletic performance-enhancing devices, all leveraging copper's antimicrobial properties to address specific health concerns.

Novelty and Inventive Step

The new claims introduce a paradigm shift by applying the core technology to entirely new fields and use cases, demonstrating a non-obvious expansion of the original patent's concepts. The inventive step lies in recognizing the broader potential of copper-based microbiome modulation and adapting it to address diverse health issues.

Alternative Embodiments and Variations

Alternative embodiments could include the use of different materials or geometries for the devices, as well as varying surface areas or configurations to optimize performance. Additionally, the concept could be extended to other health applications, such as wound healing or gastrointestinal health, further broadening its scope.

Potential Commercial Applications and Market

The copper-based microbiome modulation technology has vast commercial potential, with applications in various industries, including healthcare, wellness, sports, and cosmetics. The target market includes individuals seeking preventative measures or treatments for respiratory diseases, cognitive function, skin diseases, eye diseases, and athletic performance enhancement, as well as companies looking to integrate this technology into their products or services.

CPC Classifications

SectionClassGroup
A A61 A61K9/0039
A A61 A61F6/144
A A61 A61K33/34

Field of Art

Medical device design and microbiome modulation technologies, specifically focusing on copper-based devices for health interventions, with expertise in surface area optimization, material selection, and localized biological interactions

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device designer with advanced knowledge of materials science, microbiome interactions, and device design principles, capable of understanding antimicrobial properties and translating therapeutic concepts across different physiological systems

Obviousness Rationale

The PTD represents a predictable extension of the source patent's core technological concept of using copper-based devices to modulate microbiomes and enhance local immunity. A PHOSITA would recognize the fundamental principle of copper's antimicrobial properties as universally applicable across different bodily systems, making the translation of the original cervical device concept to respiratory, cognitive, skin, and muscular applications a logical and obvious design progression.

Obvious Combinations & Variations

Source Patent Element
Copper-based uterine cervical device with specific surface area for modifying microbiome
PTD Variation
Respiratory device with similar copper composition and surface area range targeting microbiome modification
Obviousness Reasoning
Known technique of applying antimicrobial copper principles to different physiological interfaces, with predictable results of reducing inflammatory responses
Source Patent Element
Method of maintaining device to reduce viral prevalence
PTD Variation
Wearable devices for cognitive and athletic performance enhancement using similar copper-based principles
Obviousness Reasoning
Finite set of design solutions for leveraging copper's immunomodulatory properties across different biological contexts
Source Patent Element
Surface area optimization between 418-524 mm2 for therapeutic intervention
PTD Variation
Varied surface area designs for skin patches, eye masks, and performance devices between 50-400 mm2
Obviousness Reasoning
Routine design optimization using known parameters, demonstrating predictable scaling of therapeutic device principles
Source Patent Element
Manual insertion of cervical device to modify local immunity
PTD Variation
Wearable and attachable devices across multiple body systems using similar local immunity enhancement strategy
Obviousness Reasoning
Obvious extension of core therapeutic mechanism to alternative physiological interfaces using known medical device design principles
Source Patent Element
Copper-based device for reducing HPV prevalence
PTD Variation
Generalized copper-based devices for reducing disease incidence across multiple bodily systems
Obviousness Reasoning
Predictable technological translation based on established understanding of copper's broad antimicrobial and immunomodulatory properties
35 U.S.C. § 103 Summary: Based on US Patent 11857675, the present publication demonstrates that a person having ordinary skill in the art would find the disclosed copper-based microbiome modulation devices and methods obvious, as they represent a predictable technological extension of known antimicrobial and immunomodulatory principles, utilizing routine design optimization and well-understood material science techniques to translate a specific therapeutic approach across diverse physiological contexts.

Original Patent Information

Patent NumberUS 11,857,675
TitleMethod for reducing the incidence and prevalence of human papilloma virus (HPV) and for providing protection against sexually transmitted infections