Personalized Cancer Treatment Platforms and Devices

Publication ID: 24-11857677_0005_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Personalized Cancer Treatment Platforms and Devices,” Published Technical Disclosure No. 24-11857677_0005_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857677_0005_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,677.

Summary of the Inventive Concept

The present inventive concept envisions a next-generation, AI-driven platform for personalized cancer treatment, integrating melphalan-based formulations with advanced data analytics, wearable devices, and cloud-based collaboration tools to revolutionize cancer care.

Background and Problem Solved

The original patent, 'Ready to use injectable formulations of melphalan and processes for preparation thereof', addressed the need for stable and ready-to-use melphalan formulations. However, it did not provide a comprehensive solution for personalized cancer treatment, relying on manual dosing and limited data analysis. The new inventive concept addresses this limitation by introducing AI-powered dosing algorithms, real-time patient data analysis, and collaborative research platforms to optimize treatment outcomes.

Detailed Description of the Inventive Concept

The inventive concept comprises four interconnected components: 1) AI-powered dosing algorithms that adjust melphalan-based formulations based on real-time patient data and genomic analysis, 2) modular, wearable devices for administering these formulations, featuring microfluidic systems, sensor arrays, and AI-driven control units, 3) a cloud-based platform for collaborative cancer research, enabling secure data sharing and analysis, and 4) 3D-printed, implantable devices for sustained release of melphalan-based formulations. These components work in tandem to provide personalized treatment plans, optimize treatment outcomes, and facilitate cutting-edge cancer research.

Novelty and Inventive Step

The new claims introduce a paradigm shift in cancer treatment by integrating AI, wearable devices, and cloud-based platforms, which is not obvious from the original patent. The inventive concept's novelty lies in its ability to adapt to changing patient conditions, optimize treatment outcomes, and facilitate collaborative research, thereby providing a more effective and personalized approach to cancer care.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different AI algorithms, various wearable device designs, and alternative cloud-based platforms. Additionally, the inventive concept could be adapted for other types of cancer treatments, expanding its commercial potential.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the cancer treatment market, with potential applications in personalized medicine, precision oncology, and collaborative cancer research. The market for AI-driven healthcare solutions is expected to grow substantially, and the inventive concept is well-positioned to capitalize on this trend.

CPC Classifications

SectionClassGroup
A A61 A61K9/08
A A61 A61K9/0019
A A61 A61K31/198
A A61 A61K47/10
A A61 A61K47/183
A A61 A61K47/32

Field of Art

Pharmaceutical formulations, drug delivery systems, and medical device technologies with a focus on oncological treatments and personalized medicine

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degrees in pharmaceutical sciences, biomedical engineering, or related fields, possessing expertise in drug formulation, medical device design, and emerging technologies like AI-driven healthcare solutions

Obviousness Rationale

A PHOSITA would recognize that integrating AI-powered analytics, personalized dosing algorithms, and advanced drug delivery mechanisms with existing melphalan formulations represents a predictable technological evolution. The source patent establishes a stable melphalan formulation, which naturally invites optimization through emerging digital health technologies. The disclosed variations demonstrate standard technological progression by applying known computational and engineering techniques to enhance pharmaceutical treatment strategies.

Obvious Combinations & Variations

Source Patent Element
Stable liquid parenteral melphalan formulation with specific concentration ranges
PTD Variation
AI-powered dosing algorithm dynamically adjusting melphalan concentration based on patient genomic data
Obviousness Reasoning
Personalized medicine approaches are well-established, and applying computational methods to pharmaceutical dosing represents a predictable application of known techniques in precision healthcare
Source Patent Element
Injectable pharmaceutical formulation
PTD Variation
Modular wearable device with microfluidic systems for controlled melphalan administration
Obviousness Reasoning
Advanced drug delivery systems that provide precise, controlled release are a known technological progression in pharmaceutical engineering
Source Patent Element
Pharmaceutical composition with specific solvent compositions
PTD Variation
Cloud-based platform for collaborative research and data sharing about melphalan formulations
Obviousness Reasoning
Digital platforms for medical research collaboration represent a standard technological extension of existing pharmaceutical research methodologies
Source Patent Element
Stable liquid pharmaceutical formulation
PTD Variation
3D-printed implantable device with sustained release mechanisms for melphalan
Obviousness Reasoning
Sustained release drug delivery technologies are well-known in the art, and 3D printing represents a predictable manufacturing innovation for medical devices
35 U.S.C. § 103 Summary: Based on US Patent 11857677 and the accompanying Published Technical Disclosure, a person having ordinary skill in the art would find the claimed innovations obvious through standard technological progression, combining known pharmaceutical formulation techniques with emerging digital health technologies to create predictable and incremental advancements in personalized cancer treatment methodologies.

Original Patent Information

Patent NumberUS 11,857,677
TitleReady to use injectable formulations of melphalan and processes for preparation thereof
Assignee(s)RK PHARMA INC.