Personalized Cannabidiol Delivery and Adaptive Emulsification

Publication ID: 24-11857678_0005_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Personalized Cannabidiol Delivery and Adaptive Emulsification,” Published Technical Disclosure No. 24-11857678_0005_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857678_0005_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,678.

Summary of the Inventive Concept

A next-generation cannabidiol delivery system that leverages adaptive surfactant ratios, real-time monitoring, and bioresponsive polymers to optimize therapeutic efficacy and individualize treatment.

Background and Problem Solved

The original self-emulsifying cannabidiol formulations patent has limitations in terms of generic surfactant ratios and lack of personalized delivery. This new concept addresses these limitations by introducing adaptive surfactant ratios, real-time monitoring, and bioresponsive polymers to create a more effective and personalized cannabidiol delivery system.

Detailed Description of the Inventive Concept

The inventive concept comprises a system for personalized cannabidiol delivery, featuring a self-emulsifying composition with adaptive surfactant ratios tailored to an individual's gastrointestinal profile. This is achieved through a wearable device that tracks changes in skin impedance correlated with emulsion globule size, enabling real-time monitoring of cannabidiol absorption. Additionally, the composition includes a bioresponsive polymer that selectively releases cannabidiol in response to specific gut microbiome markers. The system also features a modular oral dosage form with varying surfactant ratios, allowing for dynamic adjustment of emulsion properties in response to changing physiological conditions. Furthermore, the system integrates artificial intelligence-driven dosing recommendations with a self-emulsifying composition optimized for personalized therapeutic efficacy.

Novelty and Inventive Step

The new claims introduce a paradigm shift in cannabidiol delivery by incorporating adaptive surfactant ratios, real-time monitoring, and bioresponsive polymers, which are not present in the original patent. These novel features enable personalized treatment and optimized therapeutic efficacy, making the original inventive concept obsolete.

Alternative Embodiments and Variations

Alternative embodiments may include using different types of bioresponsive polymers, varying the modular oral dosage form design, or incorporating additional sensors for real-time monitoring. Variations may also include adapting the system for different routes of administration, such as topical or transdermal delivery.

Potential Commercial Applications and Market

The personalized cannabidiol delivery system has significant commercial potential in the pharmaceutical and nutraceutical industries, particularly in the treatment of chronic diseases and conditions where individualized treatment is crucial. The system's adaptability and real-time monitoring capabilities also make it an attractive solution for precision medicine and personalized healthcare.

CPC Classifications

SectionClassGroup
A A61 A61K9/107
A A61 A61K9/4808
A A61 A61K9/4825
A A61 A61K31/05
A A61 A61K47/10
A A61 A61K47/14
A A61 A61K47/22

Field of Art

Pharmaceutical formulation and drug delivery systems, specifically focused on cannabidiol compositions with advanced emulsification techniques, requiring expertise in pharmaceutical chemistry, drug formulation, and biomedical engineering

Person of Ordinary Skill (PHOSITA) Profile

A pharmaceutical scientist with advanced degree (PhD/PharmD), specialized knowledge in drug delivery systems, emulsification techniques, surfactant interactions, and experience in developing personalized drug formulations

Obviousness Rationale

A PHOSITA would recognize that the PTD's adaptive surfactant and monitoring technologies represent predictable extensions of the source patent's self-emulsifying cannabidiol composition. The core innovation of personalized delivery builds directly upon existing emulsification principles disclosed in the original patent, utilizing known techniques of sensor integration and polymer-based drug release. The variations represent incremental improvements using standard pharmaceutical engineering approaches to enhance drug delivery precision.

Obvious Combinations & Variations

Source Patent Element
Self-emulsifying cannabidiol composition with specific surfactant ratios
PTD Variation
Adaptive surfactant ratios tailored to individual gastrointestinal profiles
Obviousness Reasoning
Predictable variation using known personalization techniques in pharmaceutical formulation, representing a design choice for optimizing drug delivery
Source Patent Element
Composition forming emulsion with 100-300 nanometer globule size
PTD Variation
Real-time monitoring of emulsion globule size using skin impedance tracking
Obviousness Reasoning
Known technique of incorporating sensor technologies to monitor pharmaceutical formulation characteristics, representing an obvious extension of existing emulsification monitoring approaches
Source Patent Element
Cannabidiol composition with multiple surfactants and additives
PTD Variation
Bioresponsive polymer for selective cannabidiol release based on gut microbiome markers
Obviousness Reasoning
Predictable application of responsive polymer technologies in drug delivery, representing a finite solution to improving targeted drug release mechanisms
Source Patent Element
Cannabidiol composition with variable surfactant combinations
PTD Variation
Modular oral dosage form with dynamically adjustable emulsion properties
Obviousness Reasoning
Obvious design modification using standard pharmaceutical engineering principles of formulation flexibility and personalized medicine approaches
35 U.S.C. § 103 Summary: Pursuant to 35 U.S.C. ยง 103, the variations disclosed in this Published Technical Disclosure would be considered obvious to a Person Having Ordinary Skill In The Art in view of US Patent 11857678, as the claimed innovations represent predictable extensions of existing self-emulsifying cannabidiol composition technologies through standard pharmaceutical engineering techniques of personalization, monitoring, and adaptive drug delivery.

Original Patent Information

Patent NumberUS 11,857,678
TitleSelf-emulsifying cannabidiol formulations
Assignee(s)Benuvia Operations, LLC