Synergistic Cannabidiol Systems for Enhanced Efficacy and Personalized Medicine

Publication ID: 24-11857678_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Cannabidiol Systems for Enhanced Efficacy and Personalized Medicine,” Published Technical Disclosure No. 24-11857678_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857678_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,678.

Summary of the Inventive Concept

The present inventive concept integrates self-emulsifying cannabidiol formulations with advanced technologies such as AI, IoT, blockchain, and new materials to create a powerful system for treating diseases and providing personalized medicine.

Background and Problem Solved

The original patent for self-emulsifying cannabidiol formulations provided a significant improvement in bioavailability and stability. However, the patent had limitations in terms of dosage optimization, patient monitoring, and secure data management. The present inventive concept addresses these limitations by incorporating synergistic combinations of technologies to create a more comprehensive and effective system.

Detailed Description of the Inventive Concept

The inventive concept comprises a self-emulsifying cannabidiol composition, which is integrated with AI-powered diagnosis tools to optimize dosage based on patient medical history and genetic profile. Additionally, the system incorporates blockchain technology to securely store and track patient medical records and treatment outcomes. Furthermore, IoT sensors are used to monitor cannabidiol levels in the patient's bloodstream and provide real-time feedback. The system also includes a smart packaging system with embedded sensors and blockchain-based tracking to ensure the authenticity and provenance of the composition. Finally, the inventive concept includes a 3D-printed oral delivery system with a built-in IoT sensor to monitor patient compliance and improve bioavailability.

Novelty and Inventive Step

The new claims introduce a novel combination of self-emulsifying cannabidiol formulations with AI, IoT, blockchain, and new materials, providing a synergistic system that is not obvious from the original patent. The inventive concept's novelty lies in its ability to integrate these distinct technologies to provide a more effective and personalized treatment approach.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different AI algorithms, IoT sensors, or blockchain platforms. Variations could also include the integration of additional technologies, such as machine learning or robotics, to further enhance the system's capabilities.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the pharmaceutical and healthcare industries, particularly in the areas of personalized medicine, disease treatment, and patient monitoring. The system's ability to provide optimized dosage, secure data management, and real-time feedback makes it an attractive solution for healthcare providers and patients alike.

CPC Classifications

SectionClassGroup
A A61 A61K9/107
A A61 A61K9/4808
A A61 A61K9/4825
A A61 A61K31/05
A A61 A61K47/10
A A61 A61K47/14
A A61 A61K47/22

Field of Art

Pharmaceutical formulation and drug delivery systems, specifically focused on cannabidiol compositions, self-emulsifying drug delivery systems (SEDDS), and personalized medicine technologies

Person of Ordinary Skill (PHOSITA) Profile

A professional with expertise in pharmaceutical sciences, having advanced degrees in pharmacy, chemical engineering, or biomedical engineering, with knowledge of drug formulation techniques, emulsion technologies, and emerging digital health platforms

Obviousness Rationale

A PHOSITA would recognize that integrating digital technologies with pharmaceutical formulations is a predictable extension of existing drug delivery research. The combination of self-emulsifying cannabidiol compositions with AI, IoT, and blockchain represents an incremental technological advancement using known techniques from pharmaceutical and digital health domains. The source patent's focus on optimized cannabidiol delivery provides a clear technical foundation for exploring enhanced monitoring and personalization strategies.

Obvious Combinations & Variations

Source Patent Element
Self-emulsifying cannabidiol composition with specific surfactant ratios and globule size characteristics
PTD Variation
Adding IoT sensors to monitor cannabidiol blood levels and AI-powered dosage optimization
Obviousness Reasoning
Monitoring drug concentration and personalizing dosage are well-established pharmaceutical engineering practices, making this integration a predictable design choice for improving treatment efficacy
Source Patent Element
Cannabidiol composition with antioxidant components
PTD Variation
Incorporating blockchain technology for tracking composition authenticity and patient treatment records
Obviousness Reasoning
Provenance tracking and secure medical record management are known techniques in digital health, representing a straightforward technological extension of existing pharmaceutical documentation practices
Source Patent Element
Composition designed for aqueous dispersion in gastric fluid
PTD Variation
3D-printed oral delivery system with embedded IoT compliance monitoring
Obviousness Reasoning
Customized drug delivery systems and patient compliance tracking are predictable innovations in personalized medicine, utilizing established manufacturing and monitoring technologies
Source Patent Element
Cannabidiol formulation with specific surfactant and oil combinations
PTD Variation
AI-powered diagnosis tool for determining optimal dosage based on genetic profile
Obviousness Reasoning
Precision medicine approaches that integrate genetic information with drug dosing are emerging standard practices in pharmaceutical research, representing an obvious technological progression
Source Patent Element
Self-emulsifying composition with defined globule size parameters
PTD Variation
Smart packaging with embedded sensors for stability monitoring
Obviousness Reasoning
Quality control technologies for pharmaceutical products, including real-time stability monitoring, are well-known techniques in drug development and manufacturing
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857678 and the published technical disclosure, a person having ordinary skill in the art would find the claimed innovations involving AI-powered dosage optimization, blockchain tracking, and IoT-enabled drug delivery systems to be obvious variations of existing self-emulsifying cannabidiol composition technologies. The combination represents a predictable application of known digital health monitoring techniques to established pharmaceutical formulation strategies, thereby rendering potential patent claims obvious and anticipatable as prior art.

Original Patent Information

Patent NumberUS 11,857,678
TitleSelf-emulsifying cannabidiol formulations
Assignee(s)Benuvia Operations, LLC