Nanoparticles carrying antibiotics for specialized environments
Legal Citation
Summary of the Inventive Concept
A system for delivering antibiotics in high-security, disaster relief, extreme weather, high-altitude, and limited access environments, utilizing nanoparticles carrying antibiotics with tailored coatings, stabilizers, and administration methods to address specific challenges.
Background and Problem Solved
The original patent disclosed nanoparticles carrying antibiotics for general antibacterial applications. However, the growing need for specialized solutions in niche environments, such as high-security facilities, disaster relief scenarios, extreme weather conditions, high-altitude regions, and areas with limited access to medical facilities, necessitates the development of adapted antibiotic delivery systems. The new inventive concept addresses these limitations by providing tailored solutions for these specific environments.
Detailed Description of the Inventive Concept
The new inventive concept encompasses four primary embodiments: 1) a system for delivering antibiotics in high-security environments, featuring tamper-evident coatings and light-activated release mechanisms; 2) a method for treating bacterial infections in disaster relief scenarios, utilizing stabilized aqueous emulsions with specific detergents; 3) a composition for preventing antibiotic resistance in extreme weather conditions, incorporating moisture-absorbing materials and temperature-activated release mechanisms; and 4) a kit for delivering antibiotics in high-altitude environments, including oxygen-stable solvents and specialized administration instructions.
Novelty and Inventive Step
The new claims introduce novel and non-obvious features, such as tamper-evident coatings, light-activated release mechanisms, and moisture-absorbing materials, which distinguish the inventive concept from the original patent and provide a unique solution for specialized environments.
Alternative Embodiments and Variations
Alternative embodiments could include the use of different nanoparticle materials, varied coating compositions, or alternative administration methods, such as aerosol delivery or implantable devices, to further broaden the conceptual coverage.
Potential Commercial Applications and Market
The inventive concept has significant commercial potential in various industries, including pharmaceuticals, biotechnology, and medical devices, with target markets including high-security facilities, disaster relief organizations, and healthcare providers operating in extreme environments.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K9/1075 |
| A | A61 | A61K31/496 |
| A | A61 | A61K47/20 |
| A | A61 | A61K47/552 |
| A | A61 | A61K47/58 |
| A | A61 | A61K47/6907 |
| A | A61 | A61P31/04 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Pharmaceutical nanotechnology and drug delivery systems, specifically focused on antibiotic encapsulation and targeted delivery mechanisms, requiring expertise in polymer chemistry, pharmaceutical formulation, and nanoscale drug engineering
Person of Ordinary Skill (PHOSITA) Profile
A researcher with advanced degrees in pharmaceutical sciences or chemical engineering, possessing knowledge of nanoparticle synthesis, drug encapsulation techniques, and experience with polymer-based drug delivery systems
Obviousness Rationale
A person having ordinary skill in the art would recognize that the PTD's variations represent predictable extensions of the source patent's core nanoparticle antibiotic delivery methodology. The fundamental approach of creating aqueous nanoparticle emulsions for antibiotic delivery remains consistent, with the PTD introducing contextual modifications that would be considered routine design variations by a skilled practitioner. The specialized environment adaptations represent logical problem-solving approaches using known techniques in nanoparticle engineering.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,679 |
|---|---|
| Title | Nanoparticles carrying antibiotics |
| Assignee(s) | University of South Florida |