Liposomal Composition for Agricultural and Veterinary Applications

Publication ID: 24-11857680_0007_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Liposomal Composition for Agricultural and Veterinary Applications,” Published Technical Disclosure No. 24-11857680_0007_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857680_0007_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,680.

Summary of the Inventive Concept

This inventive concept leverages the core technology of docetaxel liposomes to target pest cells, fungal infections, parasitic infections, and aquaculture diseases in agricultural and veterinary fields, offering a novel solution for these industries.

Background and Problem Solved

The original patent focused on developing docetaxel liposomes for cancer treatment, but its limitations in terms of targeting and delivery can be overcome by applying this technology to other industries. The new inventive concept addresses the need for effective solutions in agricultural pest control, veterinary medicine, and aquaculture.

Detailed Description of the Inventive Concept

The liposomal composition consists of docetaxel, Soya Phosphatidyl Choline, Sodium Cholesteryl Sulfate, and Sucrose, with specific weight percentages and pH adjustments. This composition is designed to target pest cells, fungal infections, parasitic infections, and aquaculture diseases, providing a targeted and efficient delivery system.

Novelty and Inventive Step

The new claims introduce a novel application of docetaxel liposomes in agricultural and veterinary fields, which is non-obvious compared to the original patent's focus on cancer treatment. The inventive step lies in adapting the liposomal composition to target specific cells and diseases in these industries.

Alternative Embodiments and Variations

Other embodiments of the inventive concept could include varying the weight percentages of the liposomal composition, adjusting the pH, or incorporating additional components to enhance targeting and delivery. These variations could be explored to further expand the scope of the inventive concept.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the agricultural and veterinary industries, offering a novel solution for pest control, fungal infections, parasitic infections, and aquaculture diseases. The target market includes companies involved in agricultural pest control, veterinary medicine, and aquaculture, as well as research institutions exploring new applications for liposomal technology.

CPC Classifications

SectionClassGroup
A A61 A61K9/127
A A61 A61K9/0019
A A61 A61K9/1277
A A61 A61K31/337
A A61 A61K47/24
A A61 A61K47/26
A A61 A61K47/28

Field of Art

Pharmaceutical formulation and drug delivery systems, specifically liposomal compositions for targeted drug delivery across medical and agricultural applications, with expertise in lipid-based drug encapsulation techniques and formulation optimization

Person of Ordinary Skill (PHOSITA) Profile

A pharmaceutical scientist or formulation engineer with advanced degrees in chemistry or pharmaceutical sciences, experienced in liposomal drug delivery, familiar with drug encapsulation techniques, solvent interactions, and cross-industry drug application strategies

Obviousness Rationale

A PHOSITA would recognize that the core liposomal composition from the source patent (US 11857680) represents a versatile drug delivery platform that can be readily adapted to different target applications by modifying the intended use while maintaining substantially identical formulation parameters. The technical variations proposed in the PTD represent predictable extensions of the original liposomal technology, utilizing known lipid encapsulation principles to target alternative cellular environments beyond oncological treatments.

Obvious Combinations & Variations

Source Patent Element
Docetaxel liposomal composition with specific weight percentages of phospholipids and stabilizing agents
PTD Variation
Applying identical liposomal composition to agricultural pest control and veterinary disease treatment
Obviousness Reasoning
Known drug delivery platforms can be repurposed across biological systems using predictable formulation techniques, representing a standard design choice for a PHOSITA
Source Patent Element
Precise weight percentages of docetaxel (0.8-1% w/w), Soya Phosphatidyl Choline (30-38% w/w), and Sodium Cholesteryl Sulfate (0.2-0.8% w/w)
PTD Variation
Maintaining identical compositional ranges while targeting fungal infections, parasitic diseases, and aquaculture applications
Obviousness Reasoning
Liposomal delivery mechanisms are fundamentally transferable across biological contexts when core formulation parameters remain consistent
Source Patent Element
pH-adjusted liposomal composition optimized for drug stability
PTD Variation
Preserving pH parameters (around 3) while expanding application domains beyond oncological treatments
Obviousness Reasoning
pH optimization represents a known technique for maintaining drug stability, and a PHOSITA would recognize the potential for cross-domain application
Source Patent Element
Targeted cellular delivery mechanism using liposomal encapsulation
PTD Variation
Extending targeting strategy from cancer cells to pest cells, fungal infections, and parasitic environments
Obviousness Reasoning
Liposomal targeting is a generalized drug delivery approach adaptable to various cellular environments through predictable formulation adjustments
Source Patent Element
Specific liposomal composition with defined weight percentages
PTD Variation
Introducing minor variations in component ratios while maintaining core formulation principles
Obviousness Reasoning
Routine optimization and slight compositional modifications represent standard engineering practices in pharmaceutical formulation
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857680, the present publication demonstrates that the claimed liposomal compositions represent obvious variations to a Person Having Ordinary Skill In The Art, as the core technical elements of drug encapsulation, compositional ranges, and targeting mechanisms remain substantially unchanged when applied to alternative biological contexts, thereby rendering potential claims to such variations unpatentable under 35 U.S.C. ยง 103.

Original Patent Information

Patent NumberUS 11,857,680
TitleComposition of docetaxel liposomal injection with high drug loading
Assignee(s)SHILPA MEDICARE LIMITED