RNA-based Solutions for Diverse Industries
Legal Citation
Summary of the Inventive Concept
This inventive concept leverages lipid-formulated RNA encoding immunogens to address unmet needs in personalized nutrition, environmental monitoring, bioterrorism detection, crop optimization, and neurological disorder treatment.
Background and Problem Solved
The original patent disclosed lipid formulations with RNA encoding immunogens for immunization. However, these formulations had limited applications. The new claims address this limitation by applying the core technology to diverse industries, solving problems such as tailored nutrition, pollution monitoring, bioterrorism detection, crop yield optimization, and neurological disorder treatment.
Detailed Description of the Inventive Concept
The inventive concept comprises RNA molecules encoding immunogens formulated with lipid particles, which are administered to stimulate an immune response tailored to specific needs. In personalized nutrition, the RNA molecules are used to stimulate an immune response that addresses individual health needs. In environmental monitoring, the RNA molecules detect changes in immune responses of aquatic organisms to determine pollution levels. In bioterrorism detection, the RNA molecules trigger an immune response specific to bioterrorism agents. In crop optimization, the RNA molecules stimulate plant immune responses to enhance resistance to disease and pests. In neurological disorders, the RNA molecules stimulate an immune response in the brain to treat disorders.
Novelty and Inventive Step
The new claims introduce a novel application of lipid-formulated RNA encoding immunogens to diverse industries, which is non-obvious and unforeseen from the original patent. The inventive step lies in recognizing the potential of this technology to solve problems beyond immunization.
Alternative Embodiments and Variations
Alternative embodiments may include different types of RNA molecules, lipid particles, or delivery systems. Variations may involve using different immunogens or targeting different industries, such as cosmetics or veterinary medicine.
Potential Commercial Applications and Market
The inventive concept has significant commercial potential in various industries, including healthcare, agriculture, environmental monitoring, and biodefense. The market size for these applications is substantial, with potential for growth and expansion into new areas.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K9/127 |
| A | A61 | A61K9/1272 |
| A | A61 | A61K31/7088 |
| A | A61 | A61K39/00 |
| A | A61 | A61K39/12 |
| C | C12 | C12N15/86 |
| A | A61 | A61K39/39 |
| A | A61 | A61K2039/53 |
| A | A61 | A61K2039/55555 |
| C | C12 | C12N2710/16134 |
| C | C12 | C12N2760/18534 |
| C | C12 | C12N2770/36134 |
Original Patent Information
| Patent Number | US 11,857,681 |
|---|---|
| Title | Lipid formulations with RNA encoding immunogens |
| Assignee(s) | GlaxoSmith Kline Biologicals S.A. |