Modified Hyaluronate Compositions for Diverse Industrial Applications

Publication ID: 24-11857682_0007_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Modified Hyaluronate Compositions for Diverse Industrial Applications,” Published Technical Disclosure No. 24-11857682_0007_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857682_0007_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,682.

Summary of the Inventive Concept

Expanding the scope of modified hyaluronate compositions to address pressing environmental and industrial challenges, leveraging the core technology to develop innovative solutions for wastewater treatment, sustainable agriculture, coral reef restoration, biodegradable plastics, and contaminated soil remediation.

Background and Problem Solved

The original patent focused on soft tissue fillers, but the modified hyaluronate compositions can be repurposed to tackle significant environmental and industrial problems. The new inventive concept addresses the limitations of traditional approaches in these fields, such as ineffective pollutant removal, unsustainable agricultural practices, and inadequate coral reef restoration methods.

Detailed Description of the Inventive Concept

The modified hyaluronate compositions are adapted for use in various industrial applications. In wastewater treatment, the composition filters out heavy metals and pollutants. In sustainable agriculture, it is mixed with nutrients to create a slow-release fertilizer promoting healthy plant growth. For coral reef restoration, the composition serves as a matrix for coral growth. In biodegradable plastics, it is incorporated into a bioplastic material. Finally, in contaminated soil remediation, the composition absorbs and breaks down pollutants. Each application leverages the unique properties of the modified hyaluronate compositions to provide innovative solutions.

Novelty and Inventive Step

The new claims introduce a paradigm shift in the application of modified hyaluronate compositions, moving beyond soft tissue fillers to address critical environmental and industrial challenges. The inventive step lies in the unexpected yet effective use of these compositions in diverse fields, offering a new perspective on solving pressing problems.

Alternative Embodiments and Variations

Alternative embodiments may include varying the concentration or composition of the modified hyaluronate, combining it with other materials or additives, or adapting the manufacturing process to suit specific industrial applications. Variations could also involve using different types of hyaluronic acid or modifying the crosslinking process to enhance the composition's properties.

Potential Commercial Applications and Market

The modified hyaluronate compositions have significant commercial potential in various industries, including wastewater treatment, agriculture, environmental remediation, and bioplastics. The target markets include companies and organizations seeking innovative, sustainable solutions to pressing environmental and industrial challenges.

CPC Classifications

SectionClassGroup
A A61 A61K9/1652
A A61 A61K8/735
A A61 A61K9/0019
A A61 A61K9/06
A A61 A61K9/1658
A A61 A61K31/167
A A61 A61K47/42
A A61 A61Q19/08

Field of Art

Biomaterials and pharmaceutical compositions, specifically hyaluronic acid-based formulations with expertise in chemical modification, crosslinking techniques, and advanced material applications

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degrees in chemistry, biochemistry, or materials science, possessing knowledge of polymer chemistry, biomaterial engineering, and industrial application strategies for modified biomolecules

Obviousness Rationale

A PHOSITA would recognize that the fundamental properties of modified hyaluronate compositions disclosed in US 11857682 inherently suggest broader applications beyond soft tissue fillers. The source patent's detailed crosslinking and modification techniques provide a clear technological foundation that would naturally inspire exploration of alternative industrial uses. The compositional characteristics described in the original patent, such as specific molecular weight, crosslinking ratios, and particle size, are directly transferable to diverse environmental and industrial contexts.

Obvious Combinations & Variations

Source Patent Element
Crosslinked hyaluronic acid composition with controlled particle size and molecular characteristics
PTD Variation
Application of modified hyaluronate in wastewater treatment for heavy metal filtration
Obviousness Reasoning
Known adsorption properties of modified polymers make heavy metal removal a predictable and logical extension of the original composition's technical capabilities
Source Patent Element
Method of preparing hyaluronate solution with specific salt concentrations and crosslinking parameters
PTD Variation
Incorporation of modified hyaluronate into slow-release agricultural fertilizer matrix
Obviousness Reasoning
Polymer encapsulation and controlled release are standard techniques in materials science, making this adaptation an obvious design choice for a skilled practitioner
Source Patent Element
Hyaluronate composition with local anesthetic additives demonstrating material versatility
PTD Variation
Use of modified hyaluronate as a biodegradable plastic alternative
Obviousness Reasoning
The source patent's emphasis on material modification inherently suggests potential for creating alternative material structures with similar base chemistry
Source Patent Element
Crosslinking method producing hyaluronate with specific rheological properties
PTD Variation
Coral reef restoration matrix utilizing modified hyaluronate composition
Obviousness Reasoning
The material's inherent biocompatibility and structural properties make its application in ecological restoration a predictable technological progression
35 U.S.C. § 103 Summary: Based on the teachings of US 11857682, a person of ordinary skill in the art would find the disclosed industrial and environmental applications of modified hyaluronate compositions to be obvious variations that follow directly from the source patent's comprehensive description of hyaluronic acid modification techniques. The PTD represents an expected technological extension demonstrating no inventive step beyond the existing knowledge in biomaterial engineering and polymer chemistry.

Original Patent Information

Patent NumberUS 11,857,682
TitleHyaluronate compositions and soft tissue fillers
Assignee(s)AMC