Specialized Hyaluronate Compositions for Niche Applications
Legal Citation
Summary of the Inventive Concept
This inventive concept adapts hyaluronate compositions for specific, narrow markets or unique operational environments, such as disaster relief, high-security facial recognition, extreme weather conditions, space exploration, and remote medical treatment.
Background and Problem Solved
The original patent disclosed hyaluronate compositions and soft tissue fillers, but it did not address the need for specialized variations that cater to unique requirements. This inventive concept solves the problem of limited adaptability by providing modified hyaluronate compositions tailored to specific niche applications.
Detailed Description of the Inventive Concept
The new inventive concept comprises modified hyaluronate compositions prepared in unbuffered 135 mM to 200 mM NaCl, which can be crosslinked to minimize swelling, and may include local anesthetics for pain relief. The compositions can be designed for specific applications, such as disaster relief, high-security facial recognition, extreme weather conditions, space exploration, and remote medical treatment. For instance, the composition for disaster relief includes a local anesthetic for pain relief, while the composition for high-security facial recognition is crosslinked to minimize swelling. The composition for extreme weather conditions is a topical anesthetic gel, and the composition for space exploration has an average particle size of less than about 2 μm.
Novelty and Inventive Step
The new claims introduce novel and non-obvious modifications to the original hyaluronate compositions, including the use of local anesthetics, crosslinking to minimize swelling, and preparation in microgravity conditions. These modifications provide a significant inventive step over the original patent, enabling the compositions to address specific niche applications.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include modifying the composition for use in other niche applications, such as search and rescue operations, environmental monitoring, or veterinary medicine. Variations could also include different crosslinking agents, particle sizes, or local anesthetics to further tailor the composition to specific requirements.
Potential Commercial Applications and Market
The inventive concept has significant commercial potential in various industries, including disaster relief, biometrics, pharmaceuticals, aerospace, and healthcare. The modified hyaluronate compositions could be marketed as specialized products for specific niche applications, providing a competitive advantage in these markets.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K9/1652 |
| A | A61 | A61K8/735 |
| A | A61 | A61K9/0019 |
| A | A61 | A61K9/06 |
| A | A61 | A61K9/1658 |
| A | A61 | A61K31/167 |
| A | A61 | A61K47/42 |
| A | A61 | A61Q19/08 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Biomaterials and pharmaceutical compositions, specifically hyaluronate-based tissue engineering and medical formulations, with expertise in chemical modification, crosslinking techniques, and targeted drug delivery systems
Person of Ordinary Skill (PHOSITA) Profile
A professional with advanced degrees in biochemistry, materials science, or pharmaceutical chemistry, possessing knowledge of polymer chemistry, medical device development, and biomaterial modification techniques
Obviousness Rationale
A person of ordinary skill would recognize that the source patent's hyaluronate composition provides a foundational framework that can be readily adapted to specialized applications by applying known modification techniques. The PTD's variations represent predictable extensions of the original patent's teachings, utilizing standard crosslinking, anesthetic incorporation, and particle size optimization methods that are well-established in the biomaterials field.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,682 |
|---|---|
| Title | Hyaluronate compositions and soft tissue fillers |
| Assignee(s) | AMC |