Specialized Hyaluronate Compositions for Niche Applications

Publication ID: 24-11857682_0009_PTD
Published: October 28, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Specialized Hyaluronate Compositions for Niche Applications,” Published Technical Disclosure No. 24-11857682_0009_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857682_0009_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,682.

Summary of the Inventive Concept

This inventive concept adapts hyaluronate compositions for specific, narrow markets or unique operational environments, such as disaster relief, high-security facial recognition, extreme weather conditions, space exploration, and remote medical treatment.

Background and Problem Solved

The original patent disclosed hyaluronate compositions and soft tissue fillers, but it did not address the need for specialized variations that cater to unique requirements. This inventive concept solves the problem of limited adaptability by providing modified hyaluronate compositions tailored to specific niche applications.

Detailed Description of the Inventive Concept

The new inventive concept comprises modified hyaluronate compositions prepared in unbuffered 135 mM to 200 mM NaCl, which can be crosslinked to minimize swelling, and may include local anesthetics for pain relief. The compositions can be designed for specific applications, such as disaster relief, high-security facial recognition, extreme weather conditions, space exploration, and remote medical treatment. For instance, the composition for disaster relief includes a local anesthetic for pain relief, while the composition for high-security facial recognition is crosslinked to minimize swelling. The composition for extreme weather conditions is a topical anesthetic gel, and the composition for space exploration has an average particle size of less than about 2 μm.

Novelty and Inventive Step

The new claims introduce novel and non-obvious modifications to the original hyaluronate compositions, including the use of local anesthetics, crosslinking to minimize swelling, and preparation in microgravity conditions. These modifications provide a significant inventive step over the original patent, enabling the compositions to address specific niche applications.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include modifying the composition for use in other niche applications, such as search and rescue operations, environmental monitoring, or veterinary medicine. Variations could also include different crosslinking agents, particle sizes, or local anesthetics to further tailor the composition to specific requirements.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in various industries, including disaster relief, biometrics, pharmaceuticals, aerospace, and healthcare. The modified hyaluronate compositions could be marketed as specialized products for specific niche applications, providing a competitive advantage in these markets.

CPC Classifications

SectionClassGroup
A A61 A61K9/1652
A A61 A61K8/735
A A61 A61K9/0019
A A61 A61K9/06
A A61 A61K9/1658
A A61 A61K31/167
A A61 A61K47/42
A A61 A61Q19/08

Original Patent Information

Patent NumberUS 11,857,682
TitleHyaluronate compositions and soft tissue fillers
Assignee(s)AMC