Collagenase-based Solutions for Industrial and Environmental Applications

Publication ID: 24-11857685_0007_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Collagenase-based Solutions for Industrial and Environmental Applications,” Published Technical Disclosure No. 24-11857685_0007_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857685_0007_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,685.

Summary of the Inventive Concept

The inventive concept leverages the core technology of collagenase-based treatment for uterine fibroids to address unmet needs in various industries, including paper production, textile manufacturing, soil erosion prevention, industrial equipment maintenance, and biofuel generation.

Background and Problem Solved

The original patent disclosed a method for treating uterine fibroids using purified collagenase. However, the potential applications of collagenase extend far beyond medical treatments. This inventive concept addresses the limitations of the original patent by exploring new use cases for collagenase in industrial and environmental contexts, where its unique properties can provide significant benefits.

Detailed Description of the Inventive Concept

The new claims describe various systems, methods, and compositions that utilize collagenase to break down and recycle cellulose fibers in waste paper, degrade and recycle keratin-based materials, stabilize soil particles, remove stubborn deposits of collagen-rich substances, and convert collagen-rich biomass into fermentable sugars. These applications take advantage of collagenase's ability to selectively degrade collagen-rich materials, offering a sustainable and efficient solution for various industries.

Novelty and Inventive Step

The new claims introduce a novel and non-obvious application of collagenase-based technology, departing from the original patent's medical focus. The inventive step lies in recognizing the potential of collagenase to address specific challenges in industrial and environmental contexts, and developing tailored solutions to capitalize on this potential.

Alternative Embodiments and Variations

Alternative embodiments may include using different sources of collagenase, such as bacterial or fungal-derived enzymes, or combining collagenase with other enzymes or agents to enhance its effectiveness. Variations may also involve adapting the collagenase-based solutions for use in other industries, such as wastewater treatment or bioremediation.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in various industries, including paper and pulp, textiles, construction, and bioenergy. The market for collagenase-based solutions is expected to grow as companies seek sustainable and efficient solutions to reduce waste, increase productivity, and promote environmental stewardship.

CPC Classifications

SectionClassGroup
A A61 A61K9/48
A A61 A61K9/0019
A A61 A61K9/0034
A A61 A61K9/1075
A A61 A61K38/43
A A61 A61K38/4886
A A61 A61K45/06
C C12 C12Y304/24003

Original Patent Information

Patent NumberUS 11,857,685
TitleTreatment method and product for uterine fibroids using purified collagenase
Assignee(s)Duke University, BioSpecifics Technologies LLC