Enhanced Medical Sealant Glue for Accelerated Wound Healing

Publication ID: 24-11857693_0001_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Medical Sealant Glue for Accelerated Wound Healing,” Published Technical Disclosure No. 24-11857693_0001_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857693_0001_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,693.

Summary of the Inventive Concept

An advanced medical sealant glue capable of promoting wound healing, featuring antimicrobial properties, controlled release, and pain relief, to provide a more efficient and comfortable wound healing experience.

Background and Problem Solved

The original medical sealant glue patent has limitations in terms of wound healing efficiency and patient comfort. The new inventive concept addresses these limitations by introducing enhancements that accelerate wound healing, reduce microbial growth, and alleviate pain.

Detailed Description of the Inventive Concept

The enhanced medical sealant glue comprises a crosslinked compound of nucleophilic and electrophilic functional groups, supplemented with an antimicrobial agent to prevent infection. Additionally, the glue is formulated to have a controlled release of the crosslinked compound, ensuring sustained wound healing over an extended period. Furthermore, the glue incorporates a pain-relieving agent to minimize discomfort during the wound healing process. The glue can be prepared through a method involving the addition of a growth factor to enhance wound healing. A system for promoting wound healing using the glue includes a glue applicator and a wound dressing, with the glue adhering to the dressing to enhance wound healing.

Novelty and Inventive Step

The new claims introduce novel features such as antimicrobial properties, controlled release, and pain relief, which are not present in the original patent. These enhancements provide a non-obvious solution to the limitations of the original patent, resulting in a more efficient and comfortable wound healing experience.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include varying the type and concentration of antimicrobial agents, adjusting the controlled release profile, or incorporating different pain-relieving agents. Additionally, the glue could be formulated for specific wound types or applications, such as surgical wounds or chronic wounds.

Potential Commercial Applications and Market

The enhanced medical sealant glue has significant commercial potential in the wound care market, particularly in the treatment of chronic wounds, surgical wounds, and burns. The glue's antimicrobial properties, controlled release, and pain relief features make it an attractive solution for healthcare providers and patients seeking more efficient and comfortable wound healing solutions.

CPC Classifications

SectionClassGroup
A A61 A61L24/043
A A61 A61K35/28
A A61 A61L24/0005

Field of Art

Medical biotechnology, specifically wound healing materials and bioactive sealant compositions, involving advanced biomaterials, drug delivery systems, and regenerative medicine techniques

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or materials scientist with expertise in polymer chemistry, wound healing technologies, and biomaterial design, holding advanced degrees and practical experience in developing medical adhesives and drug delivery systems

Obviousness Rationale

A person having ordinary skill would recognize that enhancing the medical sealant glue with antimicrobial agents, controlled release mechanisms, and pain-relieving components represents predictable variations within the established technological framework of wound healing materials. These modifications directly address known limitations in wound treatment by leveraging standard biomedical engineering techniques of functional enhancement. The proposed variations represent logical extensions of the source patent's core technological principles.

Obvious Combinations & Variations

Source Patent Element
Crosslinked compound with nucleophilic and electrophilic functional groups for wound healing
PTD Variation
Adding antimicrobial agents to prevent wound infection during healing process
Obviousness Reasoning
Incorporating antimicrobial components is a known technique in wound healing technologies to reduce infection risks, representing a predictable solution using standard biomedical engineering methods
Source Patent Element
Exosome-based wound healing mechanism
PTD Variation
Implementing controlled release profile for sustained therapeutic effect
Obviousness Reasoning
Modifying drug delivery mechanisms to achieve sustained release is a well-established approach in biomaterial design, representing an obvious optimization strategy for wound healing technologies
Source Patent Element
Medical sealant glue with crosslinked compounds
PTD Variation
Integrating pain-relieving agents to improve patient comfort during wound healing
Obviousness Reasoning
Adding analgesic components to wound treatment materials is a predictable design choice addressing known patient discomfort issues, utilizing standard pharmaceutical incorporation techniques
Source Patent Element
Mesenchymal stem cell-derived exosome technology
PTD Variation
Developing a comprehensive wound healing system with specialized applicator and dressing
Obviousness Reasoning
Creating integrated medical systems is a routine engineering approach for improving treatment efficacy, representing an obvious combination of known medical device design principles
Source Patent Element
Polyethylene glycol-based crosslinking mechanism
PTD Variation
Incorporating growth factors to enhance wound healing performance
Obviousness Reasoning
Supplementing biomaterials with growth factors is a well-known regenerative medicine technique for improving tissue repair, representing a predictable optimization strategy
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857693 and the disclosed technical variations, a person having ordinary skill in the art would find the proposed medical sealant glue enhancements obvious and predictable. The systematic modifications to wound healing technologies represent routine engineering design choices that do not rise to the level of non-obvious innovation, thereby establishing this publication as valid prior art under 35 U.S.C. Section 103.

Original Patent Information

Patent NumberUS 11,857,693
TitleMedical sealant glue capable of promoting wound healing and preparation method thereof
Assignee(s)Shandong Branden Medical Device Co.,Ltd