Enhanced Medical Sealant Glue for Improved Wound Healing

Publication ID: 24-11857693_0006_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Medical Sealant Glue for Improved Wound Healing,” Published Technical Disclosure No. 24-11857693_0006_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857693_0006_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,693.

Summary of the Inventive Concept

The present invention relates to an improved medical sealant glue capable of promoting wound healing with enhanced gelation time, swelling ratio, mechanical properties, and bioactive peptide incorporation, thereby providing a more efficient and effective wound healing process.

Background and Problem Solved

The original patent disclosed a medical sealant glue capable of promoting wound healing. However, the original glue had limitations in terms of gelation time, swelling ratio, and mechanical properties, which hindered its widespread adoption. The present invention addresses these limitations by introducing improvements to the glue's formulation and preparation method.

Detailed Description of the Inventive Concept

The enhanced medical sealant glue comprises a crosslinked compound of a first component containing nucleophilic functional groups and a second component containing electrophilic functional groups. The glue is formulated to have improved gelation time, reduced by at least 30% compared to the original glue. Additionally, the glue is designed to have an increased swelling ratio in PBS solution, promoting wound healing. The glue may also incorporate a bioactive peptide to further enhance the wound healing process. The preparation method of the glue is optimized to reduce the gelation time and improve the swelling ratio of the resulting glue.

Novelty and Inventive Step

The present invention provides a novel and non-obvious solution to the limitations of the original medical sealant glue. The improvements in gelation time, swelling ratio, and mechanical properties, as well as the incorporation of bioactive peptides, provide a significant advancement in the field of wound healing.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept may include varying the type and concentration of the bioactive peptide, using different biocompatible fibers to reinforce the glue, or modifying the preparation method to achieve optimal gelation time and swelling ratio.

Potential Commercial Applications and Market

The enhanced medical sealant glue has significant commercial potential in the wound care industry, particularly in the treatment of chronic wounds, surgical wounds, and burns. The glue's improved properties make it an attractive solution for healthcare providers seeking to accelerate wound healing and reduce healthcare costs.

CPC Classifications

SectionClassGroup
A A61 A61L24/043
A A61 A61K35/28
A A61 A61L24/0005

Original Patent Information

Patent NumberUS 11,857,693
TitleMedical sealant glue capable of promoting wound healing and preparation method thereof
Assignee(s)Shandong Branden Medical Device Co.,Ltd