Adaptive Embolic Particles for Specialized Environments

Publication ID: 24-11857694_0004_PTD
Published: October 28, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Adaptive Embolic Particles for Specialized Environments,” Published Technical Disclosure No. 24-11857694_0004_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857694_0004_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,694.

Summary of the Inventive Concept

A system of embolic particles designed for deployment in unique operational environments, including high-altitude, emergency response, high-security, underwater, and extreme weather conditions, addressing the limitations of traditional embolic particles in these settings.

Background and Problem Solved

The original patent describes embolic particles for general medical purposes, but these particles may not be suitable for use in specialized environments. For instance, high-altitude environments require particles that expand in response to low atmospheric pressure, while emergency response situations demand rapid deployment. The new inventive concept addresses these limitations by providing adaptive embolic particles tailored to specific operational environments.

Detailed Description of the Inventive Concept

The inventive concept comprises embolic particles with unique properties and functionalities adapted to specific environments. For high-altitude embolization, the particles expand in size upon exposure to low atmospheric pressure. In emergency response situations, the particles are designed for rapid deployment through a microcatheter. The high-security embolic device features particles resistant to tampering or unauthorized access. The underwater embolization system incorporates buoyant particles that expand in response to water pressure. The extreme weather embolization method utilizes particles that withstand extreme temperatures and weather conditions. These adaptive particles can be delivered through a microcatheter, ensuring effective occlusion of vascular defects in these specialized environments.

Novelty and Inventive Step

The new claims introduce novel adaptations of embolic particles for specific operational environments, which are not obvious from the original patent. The inventive step lies in the tailored design of particles to address the unique challenges of high-altitude, emergency response, high-security, underwater, and extreme weather environments.

Alternative Embodiments and Variations

Alternative embodiments may include particles with adjustable expansion rates, particles that change shape in response to environmental cues, or particles with integrated sensors for real-time monitoring. Variations may also include different materials, shapes, or sizes of particles to accommodate diverse operational environments.

Potential Commercial Applications and Market

The adaptive embolic particles have significant commercial potential in various industries, including medical devices, emergency response, aerospace, and defense. The target market includes hospitals, emergency responders, and military organizations operating in specialized environments.

CPC Classifications

SectionClassGroup
A A61 A61L24/06
A A61 A61L24/001
C C08 C08F222/385
A A61 A61L2430/36

Field of Art

Medical device engineering, specifically interventional medical particles for vascular occlusion, requiring expertise in polymer chemistry, medical device design, and microcatheter-compatible particle fabrication

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or materials scientist with advanced degree, experience in polymer synthesis, medical device development, and understanding of microcatheter delivery systems for minimally invasive medical interventions

Obviousness Rationale

A PHOSITA would recognize that the PTD's environmental adaptations represent predictable variations of the source patent's core embolic particle technology. The fundamental design principles of size-adjustable, microcatheter-deliverable particles remain consistent across the PTD's proposed variations. The specific environmental modifications represent routine engineering adaptations that would be apparent to a skilled practitioner seeking to expand the utility of embolic particle systems.

Obvious Combinations & Variations

Source Patent Element
Particles configured to fit through microcatheter inner diameter with expandable properties
PTD Variation
High-altitude particles that expand in response to low atmospheric pressure
Obviousness Reasoning
Predictable extension of existing expansion mechanism, applying known material science principles to create pressure-responsive particle design
Source Patent Element
Embolic composition for occluding vascular defects
PTD Variation
Underwater buoyant particles that expand under water pressure
Obviousness Reasoning
Known technique of modifying particle composition to respond to environmental stimuli, representing a standard design optimization approach
Source Patent Element
Polyether macromer-based particle composition
PTD Variation
Particles with integrated sensors for real-time monitoring
Obviousness Reasoning
Routine materials engineering approach to enhance functionality through embedded sensing technologies, representing a predictable technological improvement
Source Patent Element
Microcatheter-deliverable particles with expandable properties
PTD Variation
Emergency response particles designed for rapid deployment
Obviousness Reasoning
Obvious variation addressing specific use case by modifying existing particle design parameters, representing a finite solution to a known technical problem
35 U.S.C. § 103 Summary: Based on US Patent 11857694's disclosure of embolic particles deliverable through microcatheters, the present publication demonstrates that variations addressing specific environmental conditions represent obvious extensions of the foundational particle technology. A person having ordinary skill in the art would readily conceive of adapting the core particle design to accommodate diverse operational requirements through routine engineering modifications.

Original Patent Information

Patent NumberUS 11,857,694
TitleParticles
Assignee(s)MicroVention, Inc.