Lung-like Epithelium-based Air Purification and Sensing Systems
Legal Citation
Summary of the Inventive Concept
The inventive concept leverages the core technology of growing 3-dimensional lung-like epithelium to develop novel applications in air purification, sensing, and fragrance generation, addressing critical needs in indoor air quality, pollution detection, and personalized scents.
Background and Problem Solved
The original patent disclosed methods for growing 3-dimensional lung-like epithelium for therapeutic purposes. However, the limitations of the original patent lie in its focus on medical applications, neglecting the potential of this technology in other fields. The new inventive concept addresses this limitation by exploring the application of lung-like epithelium in air purification, sensing, and fragrance generation, providing a novel solution to pressing environmental and commercial challenges.
Detailed Description of the Inventive Concept
The inventive concept encompasses systems and methods for utilizing 3-dimensional lung-like epithelium in air purification, sensing, and fragrance generation. The epithelium is cultured in a chamber, where it can interact with air, pollutants, or odor molecules. In air purification systems, the epithelium facilitates the removal of pollutants, improving indoor air quality. In sensing applications, the epithelium is coupled to sensors, enabling the detection of airborne pollutants. For fragrance generation, the epithelium responds to different odor molecules, allowing for the creation of personalized scents.
Novelty and Inventive Step
The new claims introduce a paradigm shift in the application of lung-like epithelium, transitioning from therapeutic uses to environmental and commercial applications. The inventive step lies in the recognition of the epithelium's potential in air purification, sensing, and fragrance generation, and the development of novel systems and methods to harness this potential.
Alternative Embodiments and Variations
Alternative embodiments may include the use of different types of cells or signaling pathways to generate the lung-like epithelium, or the integration of the epithelium with other technologies, such as robotics or artificial intelligence, to enhance its functionality. Variations of the inventive concept may also involve the application of lung-like epithelium in other fields, such as cosmetics or food technology.
Potential Commercial Applications and Market
The inventive concept has significant commercial potential in the air purification, sensing, and fragrance industries. The market for air purification systems is growing rapidly, driven by increasing concerns about indoor air quality. The sensing and fragrance applications also offer opportunities for growth, particularly in the fields of robotics and personalized consumer products.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61L27/3895 |
| A | A61 | A61K35/42 |
| A | A61 | A61L27/3804 |
| A | A61 | A61L27/3813 |
| A | A61 | A61L27/3834 |
| A | A61 | A61L27/3839 |
| A | A61 | A61L27/3869 |
| C | C12 | C12N5/0018 |
| C | C12 | C12N5/0062 |
| C | C12 | C12N5/0606 |
| C | C12 | C12N5/0607 |
| C | C12 | C12N5/0688 |
| C | C12 | C12N5/0689 |
| A | A61 | A61L2430/22 |
| C | C12 | C12N2501/113 |
| C | C12 | C12N2501/115 |
| C | C12 | C12N2501/117 |
| C | C12 | C12N2501/119 |
| C | C12 | C12N2501/155 |
| C | C12 | C12N2501/385 |
| C | C12 | C12N2501/415 |
| C | C12 | C12N2501/999 |
| C | C12 | C12N2506/02 |
| C | C12 | C12N2506/03 |
| C | C12 | C12N2506/27 |
| C | C12 | C12N2506/45 |
| C | C12 | C12N2513/00 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Regenerative medicine, stem cell biology, tissue engineering, with a focus on lung epithelial cell culture and differentiation techniques
Person of Ordinary Skill (PHOSITA) Profile
A biomedical researcher with advanced training in stem cell biology, cell differentiation protocols, tissue engineering, and biotechnology, possessing expertise in cell culture techniques, signaling pathway manipulation, and interdisciplinary application of cellular technologies
Obviousness Rationale
A person having ordinary skill in the art would recognize the natural extension of the source patent's lung-like epithelium cultivation techniques to novel application domains such as air purification, sensing, and fragrance generation. The fundamental cellular cultivation methodology remains consistent, with the primary innovation being the identification of alternative functional contexts for the 3-dimensional lung-like epithelium. These variations represent predictable applications of a well-characterized biological system, leveraging the inherent sensing and interactive capabilities of lung-like tissue.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,697 |
|---|---|
| Title | Compositions and methods for obtaining 3-dimensional lung-like epithelium and related uses thereof |
| Assignee(s) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN |