Enhanced Bone Graft System with Improved Bioactivity and Mechanical Strength

The present invention relates to an improved bone graft system, which enhances bioactivity and mechanical strength by incorporating surface coatings, hierarchical porous structures, and controlled release of bioactive molecules.

The original bone graft system patent has limitations in terms of bioactivity and mechanical strength. The present invention addresses these limitations by introducing novel features that improve the bone graft substitutes' performance in dental or orthopaedic implants.

The enhanced bone graft system comprises a silicate-based material with a porous structure, incorporating metal cations and having a density less than 0.7 g/cm3. The system further includes a surface coating to enhance bioactivity and cellular adhesion, a hierarchical porous structure with macroporous framework and microporous channels to enhance cellular infiltration and tissue regeneration, and a controlled release mechanism for bioactive molecules to promote tissue regeneration. The system can be customized by adjusting the mechanical properties through mechanical treatment.

The new claims introduce novel features such as surface coatings, hierarchical porous structures, and controlled release of bioactive molecules, which are not present in the original patent. These features provide an inventive step by improving the bioactivity and mechanical strength of the bone graft substitutes.

Alternative embodiments of the inventive concept could include using different types of surface coatings, varying the hierarchical porous structure's dimensions, or incorporating additional bioactive molecules. These variations would ensure broad conceptual coverage and adaptability to different implant applications.

The enhanced bone graft system has significant commercial potential in the dental and orthopaedic implant markets, where there is a growing demand for improved bone graft substitutes. The system's improved bioactivity and mechanical strength could lead to increased adoption and market share.