Adaptive Bioactive Bone Graft System

Publication ID: 24-11857698_0010_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Adaptive Bioactive Bone Graft System,” Published Technical Disclosure No. 24-11857698_0010_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857698_0010_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,698.

Summary of the Inventive Concept

A next-generation bone graft system that dynamically adapts to the surrounding tissue environment, enabling optimal tissue integration and regeneration through real-time monitoring and control.

Background and Problem Solved

The original bone graft system, while effective, has limitations in terms of its fixed porosity and density, which can lead to suboptimal tissue integration and regeneration. The new inventive concept addresses these limitations by introducing adaptive porosity, personalized material composition, and integrated sensors and microactuators, enabling a more effective and efficient bone grafting process.

Detailed Description of the Inventive Concept

The adaptive bioactive bone graft system comprises a silicate-based material with adaptive porosity, which can be dynamically adjusted in response to changes in the surrounding tissue environment. The system also includes a method for generating personalized bone graft substitutes, incorporating tailored combinations of metal cations and phosphate compounds into a silicate network with optimized porosity and density. Additionally, the system features a hybrid material combining silicate and polymer networks, providing structural integrity and enhanced biocompatibility and tissue adhesion. The system is further equipped with integrated sensors and microactuators, enabling real-time monitoring and control of the bone graft substitute, and providing feedback to clinicians for optimized treatment outcomes.

Novelty and Inventive Step

The new claims introduce several novel and non-obvious features, including adaptive porosity, personalized material composition, and integrated sensors and microactuators, which significantly depart from the fixed porosity and density of the original bone graft system.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different materials or material combinations, such as ceramic or metal-based materials, or the integration of additional features, such as antimicrobial properties or growth factor delivery systems.

Potential Commercial Applications and Market

The adaptive bioactive bone graft system has significant commercial potential in the orthopedic and dental implant markets, offering a more effective and efficient solution for bone grafting procedures. The system's ability to adapt to individual patients' needs and provide real-time feedback to clinicians could lead to improved treatment outcomes and reduced healthcare costs.

CPC Classifications

SectionClassGroup
A A61 A61L27/40
A A61 A61L27/425
A A61 A61L27/427
A A61 A61L27/52
A A61 A61L27/56
A A61 A61L2430/02

Original Patent Information

Patent NumberUS 11,857,698
TitleBone graft system
Assignee(s)UCL BUSINESS LTD