Expanding Anti-Adhesive Barrier Membrane Technology into New Applications

Publication ID: 24-11857701_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Expanding Anti-Adhesive Barrier Membrane Technology into New Applications,” Published Technical Disclosure No. 24-11857701_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857701_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,701.

Summary of the Inventive Concept

This inventive concept leverages the core technology of the original anti-adhesive barrier membrane using alginate and hyaluronic acid to address unmet needs in various industries, including medical implant infection prevention, wound healing, biosensing, controlled therapeutic release, and biofilm prevention.

Background and Problem Solved

The original patent disclosed an anti-adhesive barrier membrane using alginate and hyaluronic acid for biomedical applications. However, the membrane's potential extends beyond its initial scope. The new inventive concept tackles the limitations of the original patent by applying the core technology to novel industries and use cases, thereby expanding its commercial potential.

Detailed Description of the Inventive Concept

The new inventive concept comprises a hydrogel barrier membrane using alginate and hyaluronic acid, adapted for various applications. In the medical implant context, the membrane prevents bacterial colonization. For wound healing, the membrane promotes healing by selectively inhibiting fibroblast infiltration. As a biosensor, the membrane is functionalized with antibodies or aptamers to detect specific biomarkers. In controlled therapeutic release, the membrane is designed to release therapeutic agents in a sustained manner. Finally, the membrane inhibits bacterial adhesion and biofilm formation on medical devices.

Novelty and Inventive Step

The new claims introduce novel applications and use cases for the anti-adhesive barrier membrane technology, which were not anticipated in the original patent. The inventive step lies in the recognition of the membrane's versatility and its adaptation to address unmet needs in diverse industries.

Alternative Embodiments and Variations

Alternative embodiments may include varying the composition or structure of the hydrogel barrier membrane to optimize its performance in specific applications. Variations may also involve combining the membrane with other materials or technologies to enhance its functionality.

Potential Commercial Applications and Market

The expanded anti-adhesive barrier membrane technology has significant commercial potential in the medical device, wound care, biosensing, and pharmaceutical industries. The market for these applications is substantial, with growing demand for innovative solutions to address unmet needs.

CPC Classifications

SectionClassGroup
A A61 A61L31/041
A A61 A61K31/192
A A61 A61K31/195
A A61 A61L31/145
A A61 A61L31/148
A A61 A61L31/16
A A61 A61L2300/414
A A61 A61L2300/43
A A61 A61L2300/62

Original Patent Information

Patent NumberUS 11,857,701
TitleAnti-adhesive barrier membrane using alginate and hyaluronic acid for biomedical applications
Assignee(s)Board of Regents, The University of Texas System