Synergistic Anti-Adhesive Barrier Membrane Systems for Advanced Biomedical Applications

Publication ID: 24-11857701_0003_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Anti-Adhesive Barrier Membrane Systems for Advanced Biomedical Applications,” Published Technical Disclosure No. 24-11857701_0003_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857701_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,701.

Summary of the Inventive Concept

The present inventive concept integrates a non-toxic, anti-adhesion hydrogel barrier membrane comprising biocompatible polysaccharides (alginate and hyaluronic acid) with distinct technologies such as AI, IoT, blockchain, and new materials to create a more powerful system for biomedical applications, enhancing tissue repair, wound monitoring, and personalized tissue engineering.

Background and Problem Solved

The original patent disclosed a non-toxic, anti-adhesion hydrogel barrier membrane for biomedical applications. However, the original patent's limitations included the lack of integration with advanced technologies, limited monitoring capabilities, and no provision for personalized tissue engineering. The new inventive concept addresses these limitations by synergistically combining the hydrogel barrier membrane with AI, IoT, blockchain, and new materials to create a more comprehensive and effective system.

Detailed Description of the Inventive Concept

The new inventive concept encompasses five distinct systems: 1) an AI-powered sensor integrated with the hydrogel barrier membrane for real-time monitoring of tissue healing progress, 2) a blockchain-secured tracking system for monitoring the membrane's production, storage, and deployment history, 3) an IoT-enabled sensor integrated with the hydrogel barrier membrane for tracking wound healing progress and detecting potential complications, 4) a novel biomaterial composition combining the hydrogel barrier membrane with graphene oxide nanoparticles for enhanced mechanical strength and electrical conductivity, and 5) a machine learning algorithm integrated with the hydrogel barrier membrane for predicting optimal membrane properties and degradation profiles based on individual patient data. These systems enable advanced biomedical applications, including tissue repair, wound monitoring, and personalized tissue engineering.

Novelty and Inventive Step

The new inventive concept's novelty lies in the synergistic integration of the hydrogel barrier membrane with distinct technologies such as AI, IoT, blockchain, and new materials, providing a more comprehensive and effective system for biomedical applications. The inventive step is the unexpected combination of these technologies to create a more powerful system that enhances tissue repair, wound monitoring, and personalized tissue engineering.

Alternative Embodiments and Variations

Alternative embodiments and variations of the inventive concept may include the use of different biocompatible materials, varying the ratio of alginate to hyaluronic acid, or incorporating additional technologies such as nanotechnology or robotics. These variations can ensure broad conceptual coverage and adaptability to diverse biomedical applications.

Potential Commercial Applications and Market

The new inventive concept has significant commercial potential in the biomedical industry, particularly in the areas of tissue repair, wound monitoring, and personalized tissue engineering. The market for advanced biomedical systems is growing rapidly, driven by the need for more effective and efficient solutions for various medical applications. The inventive concept's potential to enhance tissue repair, wound monitoring, and personalized tissue engineering positions it for significant market share and revenue growth.

CPC Classifications

SectionClassGroup
A A61 A61L31/041
A A61 A61K31/192
A A61 A61K31/195
A A61 A61L31/145
A A61 A61L31/148
A A61 A61L31/16
A A61 A61L2300/414
A A61 A61L2300/43
A A61 A61L2300/62

Original Patent Information

Patent NumberUS 11,857,701
TitleAnti-adhesive barrier membrane using alginate and hyaluronic acid for biomedical applications
Assignee(s)Board of Regents, The University of Texas System