Synergistic Anti-Adhesive Barrier Membrane Systems for Advanced Biomedical Applications
Legal Citation
Summary of the Inventive Concept
The present inventive concept integrates a non-toxic, anti-adhesion hydrogel barrier membrane comprising biocompatible polysaccharides (alginate and hyaluronic acid) with distinct technologies such as AI, IoT, blockchain, and new materials to create a more powerful system for biomedical applications, enhancing tissue repair, wound monitoring, and personalized tissue engineering.
Background and Problem Solved
The original patent disclosed a non-toxic, anti-adhesion hydrogel barrier membrane for biomedical applications. However, the original patent's limitations included the lack of integration with advanced technologies, limited monitoring capabilities, and no provision for personalized tissue engineering. The new inventive concept addresses these limitations by synergistically combining the hydrogel barrier membrane with AI, IoT, blockchain, and new materials to create a more comprehensive and effective system.
Detailed Description of the Inventive Concept
The new inventive concept encompasses five distinct systems: 1) an AI-powered sensor integrated with the hydrogel barrier membrane for real-time monitoring of tissue healing progress, 2) a blockchain-secured tracking system for monitoring the membrane's production, storage, and deployment history, 3) an IoT-enabled sensor integrated with the hydrogel barrier membrane for tracking wound healing progress and detecting potential complications, 4) a novel biomaterial composition combining the hydrogel barrier membrane with graphene oxide nanoparticles for enhanced mechanical strength and electrical conductivity, and 5) a machine learning algorithm integrated with the hydrogel barrier membrane for predicting optimal membrane properties and degradation profiles based on individual patient data. These systems enable advanced biomedical applications, including tissue repair, wound monitoring, and personalized tissue engineering.
Novelty and Inventive Step
The new inventive concept's novelty lies in the synergistic integration of the hydrogel barrier membrane with distinct technologies such as AI, IoT, blockchain, and new materials, providing a more comprehensive and effective system for biomedical applications. The inventive step is the unexpected combination of these technologies to create a more powerful system that enhances tissue repair, wound monitoring, and personalized tissue engineering.
Alternative Embodiments and Variations
Alternative embodiments and variations of the inventive concept may include the use of different biocompatible materials, varying the ratio of alginate to hyaluronic acid, or incorporating additional technologies such as nanotechnology or robotics. These variations can ensure broad conceptual coverage and adaptability to diverse biomedical applications.
Potential Commercial Applications and Market
The new inventive concept has significant commercial potential in the biomedical industry, particularly in the areas of tissue repair, wound monitoring, and personalized tissue engineering. The market for advanced biomedical systems is growing rapidly, driven by the need for more effective and efficient solutions for various medical applications. The inventive concept's potential to enhance tissue repair, wound monitoring, and personalized tissue engineering positions it for significant market share and revenue growth.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61L31/041 |
| A | A61 | A61K31/192 |
| A | A61 | A61K31/195 |
| A | A61 | A61L31/145 |
| A | A61 | A61L31/148 |
| A | A61 | A61L31/16 |
| A | A61 | A61L2300/414 |
| A | A61 | A61L2300/43 |
| A | A61 | A61L2300/62 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Biomedical materials engineering, specifically biopolymer hydrogel barrier membranes for tissue repair and medical applications, requiring advanced knowledge of polymer chemistry, biomaterials science, and medical device design
Person of Ordinary Skill (PHOSITA) Profile
A biomedical engineer or materials scientist with a PhD or equivalent industry experience, familiar with polysaccharide-based hydrogels, tissue engineering techniques, and emerging medical technologies
Obviousness Rationale
A PHOSITA would recognize that integrating advanced monitoring technologies with the existing alginate-hyaluronic acid hydrogel barrier membrane represents a predictable extension of the source patent's core technology. The fundamental barrier membrane composition remains substantially unchanged, while the proposed technological integrations represent standard approaches to enhancing medical device functionality. The combination of known technologies to improve medical device performance is a typical innovation pathway in biomedical engineering.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,701 |
|---|---|
| Title | Anti-adhesive barrier membrane using alginate and hyaluronic acid for biomedical applications |
| Assignee(s) | Board of Regents, The University of Texas System |