Enhanced Insulin Delivery Rate Adjustment System

Publication ID: 24-11857763_0001_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Insulin Delivery Rate Adjustment System,” Published Technical Disclosure No. 24-11857763_0001_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857763_0001_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,763.

Summary of the Inventive Concept

An advanced insulin delivery system that leverages real-time user feedback, glucose data, and machine learning algorithms to optimize basal insulin delivery rates, minimizing hypoglycemic events and improving glucose level control.

Background and Problem Solved

The original patent, 'Adjusting insulin delivery rates,' has limitations in predicting glucose levels and adjusting insulin delivery rates accordingly. The new inventive concept addresses these limitations by introducing a fully closed-loop system that integrates real-time glucose data, user feedback, and advanced algorithms to predict and adjust insulin delivery rates, thereby minimizing hypoglycemic events and improving glucose level control.

Detailed Description of the Inventive Concept

The new inventive concept comprises a glucose measurement device, a processor, and a controller. The glucose measurement device provides up-to-date blood glucose data, which is used by the processor to predict multiple future blood glucose levels for multiple different basal insulin delivery profiles. The controller selects the optimal basal insulin delivery profile that minimizes differences between the predicted future blood glucose values and one or more target blood glucose values. The system can be part of a fully closed-loop system, automatically delivering a bolus, or a hybrid closed-loop system, adjusting basal insulin delivery rates based on user input. The system also incorporates real-time user feedback to update the basal insulin delivery profiles, ensuring personalized and adaptive insulin delivery.

Novelty and Inventive Step

The new inventive concept introduces a fully closed-loop system that integrates real-time glucose data, user feedback, and advanced algorithms to predict and adjust insulin delivery rates, thereby minimizing hypoglycemic events and improving glucose level control. The novel aspect lies in the system's ability to adapt to user feedback and update the basal insulin delivery profiles in real-time, ensuring a more personalized and effective insulin delivery system.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include using machine learning algorithms to predict glucose levels, incorporating additional health metrics, such as physical activity or sleep patterns, or integrating with wearable devices to provide more comprehensive glucose monitoring. Variations could include using different types of insulin, such as rapid-acting or long-acting insulin, or developing systems for other types of diabetes, such as type 1 or type 2 diabetes.

Potential Commercial Applications and Market

The enhanced insulin delivery rate adjustment system has significant commercial potential in the diabetes management market, which is expected to grow to $12.6 billion by 2025. The system's ability to minimize hypoglycemic events and improve glucose level control makes it an attractive solution for patients with diabetes, particularly those with type 1 diabetes. The system's adaptability and personalization capabilities also make it an attractive solution for healthcare providers and payers looking to improve patient outcomes and reduce healthcare costs.

CPC Classifications

SectionClassGroup
A A61 A61M5/1723
A A61 A61B5/14532
A A61 A61B5/4839
A A61 A61M5/142
A A61 A61M5/145
A A61 A61M5/14244
A A61 A61M5/14248
G G16 G16H20/17
G G16 G16H40/60
G G16 G16H40/67
A A61 A61B2562/0295
A A61 A61M2005/14208
A A61 A61M2205/3303
A A61 A61M2205/3553
A A61 A61M2205/3561
A A61 A61M2205/3569
A A61 A61M2205/3584
A A61 A61M2205/502
A A61 A61M2205/52
A A61 A61M2230/005
A A61 A61M2230/201
G G16 G16H10/60
G G16 G16H40/40
G G16 G16H50/30

Field of Art

Medical Device Technology - Diabetes Management Systems, specifically focusing on insulin delivery and glucose monitoring technologies involving closed-loop systems, medical data processing, and personalized metabolic intervention strategies

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device specialist with expertise in diabetes management technologies, advanced signal processing, machine learning algorithms for physiological data, and experience designing adaptive medical monitoring systems

Obviousness Rationale

A person having ordinary skill would recognize that the PTD represents a predictable extension of the source patent's insulin delivery methodology by incorporating additional real-time adaptive algorithms and user feedback mechanisms. The core technical problem of optimizing insulin delivery remains consistent, with the PTD introducing incremental improvements in personalization and closed-loop system design. These variations would be considered obvious combinations of known techniques in medical device technology, leveraging standard machine learning and data processing approaches.

Obvious Combinations & Variations

Source Patent Element
Calculating probability of achieving glucose levels below a threshold
PTD Variation
Incorporating real-time user feedback and machine learning to dynamically update insulin delivery profiles
Obviousness Reasoning
Predictable application of known adaptive algorithm techniques to improve personalized medical device performance
Source Patent Element
Insulin delivery profiles with variable baseline rates
PTD Variation
Developing fully and hybrid closed-loop systems that automatically adjust insulin delivery based on predicted glucose values
Obviousness Reasoning
Logical technological progression using standard control system design principles in medical device engineering
Source Patent Element
Calculating multiple future glucose values across different insulin delivery profiles
PTD Variation
Integrating additional health metrics like physical activity and sleep patterns to refine glucose predictions
Obviousness Reasoning
Obvious extension of existing predictive modeling techniques using known physiological correlation methods
Source Patent Element
Fear of hypoglycemia index as user input parameter
PTD Variation
Creating user interface that dynamically incorporates psychological and physiological risk assessment
Obviousness Reasoning
Standard human-centered design approach for personalized medical technology
Source Patent Element
Time-interval based insulin delivery method
PTD Variation
Implementing shorter secondary delivery intervals with more granular control mechanisms
Obviousness Reasoning
Routine engineering optimization using known control system refinement techniques
35 U.S.C. § 103 Summary: Based on a comprehensive analysis of US Patent 11857763, the present technical disclosure demonstrates that the claimed variations in insulin delivery system design would have been obvious to a person having ordinary skill in the art at the time of invention. The incremental technological improvements represent predictable combinations of known medical device engineering techniques, thereby rendering potential patent claims obvious and non-patentable under standard obviousness analysis.

Original Patent Information

Patent NumberUS 11,857,763
TitleAdjusting insulin delivery rates
Assignee(s)INSULET CORPORATION