Personalized Parameter Modeling with Synergistic Combinations

Publication ID: 24-11857765_0003_PTD
Published: November 07, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Personalized Parameter Modeling with Synergistic Combinations,” Published Technical Disclosure No. 24-11857765_0003_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857765_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,765.

Summary of the Inventive Concept

The invention integrates personalized parameter modeling with distinct technologies such as AI, IoT, blockchain, and new materials to create a more powerful and secure system for therapy management.

Background and Problem Solved

The original patent, 'Personalized parameter modeling methods and related devices and systems', provided a foundation for personalized therapy management. However, the system had limitations in terms of data security, predictive analytics, and integration with other technologies. The new inventive concept addresses these limitations by incorporating synergistic combinations of AI, IoT, blockchain, and new materials to enhance the system's capabilities and security.

Detailed Description of the Inventive Concept

The new system integrates a machine learning module with a sensing device to obtain current operational context information and historical operational context information. A blockchain-based secure data storage stores the historical operational context information and expected calibration factor models. An IoT-enabled infusion device receives calibrated measurement values and delivers fluid to the body of the patient. The system also incorporates AI-powered predictive analytics to determine expected calibration factor models and expected offset values. Additionally, the system utilizes new materials to enhance the sensing device's performance. The machine learning module updates the personalized parameter models based on new data, ensuring continuous improvement.

Novelty and Inventive Step

The new claims introduce the integration of AI, IoT, blockchain, and new materials with personalized parameter modeling, providing a novel and non-obvious solution. The inventive step lies in the synergistic combination of these technologies to create a more powerful and secure system for therapy management.

Alternative Embodiments and Variations

Alternative embodiments may include different machine learning algorithms, various IoT-enabled devices, or different blockchain-based data storage solutions. Variations may also include integrating the system with other technologies such as cloud computing or 5G networks.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the healthcare industry, particularly in the fields of diabetes management, personalized medicine, and therapy management. The system's enhanced capabilities and security features make it an attractive solution for patients, healthcare providers, and pharmaceutical companies.

CPC Classifications

SectionClassGroup
A A61 A61M5/1723
A A61 A61B5/14532
A A61 A61B5/4839
G G16 G16H10/60
G G16 G16H20/17
G G16 G16H40/40
G G16 G16H40/63
G G16 G16H50/20
G G16 G16H50/50
A A61 A61B5/0022
A A61 A61B5/02438
A A61 A61B5/7239
A A61 A61B5/7242
A A61 A61B2560/0242
A A61 A61B2562/0219
A A61 A61M5/14244
A A61 A61M2205/3569
A A61 A61M2205/502
A A61 A61M2205/52
A A61 A61M2205/70
A A61 A61M2230/005
A A61 A61M2230/06
A A61 A61M2230/201
G G16 G16H15/00

Field of Art

Medical device technology, specifically personalized parameter modeling for therapeutic devices, encompassing sensor systems, data processing, and medical device integration with advanced computational techniques

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device technologist with expertise in sensor systems, machine learning, data processing, and medical device design, holding advanced degrees and familiarity with interdisciplinary medical technology innovations

Obviousness Rationale

The PTD represents a predictable combination of known technologies within personalized medical parameter modeling, extending the source patent's core concepts through standard technological integration techniques. A PHOSITA would recognize that incorporating AI, blockchain, and IoT represents incremental improvements to existing medical device parameter modeling systems. The variations demonstrate standard engineering problem-solving approaches that would be apparent to someone skilled in medical device technology and computational systems design.

Obvious Combinations & Variations

Source Patent Element
Obtaining operational context information and calibration factor parameter models for patient-specific sensing devices
PTD Variation
Integrating machine learning algorithms to dynamically update and refine parameter models
Obviousness Reasoning
Applying machine learning to adaptive parameter modeling represents a known technique for improving predictive accuracy in sensor-based medical systems, with predictable performance enhancement results
Source Patent Element
Calibration and measurement processes for infusion devices
PTD Variation
Adding blockchain-based secure data storage and smart contract mechanisms for data management
Obviousness Reasoning
Implementing blockchain for secure medical data storage is a standard design choice for improving data integrity and access control in medical technology systems
Source Patent Element
Patient-specific parameter modeling methods
PTD Variation
Incorporating IoT-enabled devices for distributed sensing and automated fluid delivery
Obviousness Reasoning
Extending medical devices with IoT connectivity represents a predictable technological progression for improving real-time monitoring and automated therapeutic interventions
Source Patent Element
Calibration factor calculation based on operational context
PTD Variation
Integrating new materials to enhance sensing device performance characteristics
Obviousness Reasoning
Material science improvements represent a standard approach to incrementally enhancing medical device sensor capabilities through predictable engineering optimization
Source Patent Element
Measurement offset modeling for patient-specific contexts
PTD Variation
Implementing AI-powered predictive analytics for more sophisticated parameter modeling
Obviousness Reasoning
Applying advanced computational techniques to medical device parameter modeling is a known method for improving diagnostic and therapeutic precision
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857765 and the disclosed technological variations, a person having ordinary skill in the art would find the claimed innovations obvious and lacking non-obvious inventive merit. The incremental technological integrations represent predictable combinations of known techniques in medical device parameter modeling, demonstrating that the claimed subject matter fails to meet the non-obviousness requirements under 35 U.S.C. ยง 103.

Original Patent Information

Patent NumberUS 11,857,765
TitlePersonalized parameter modeling methods and related devices and systems
Assignee(s)MEDTRONIC MINIMED, INC.