Synergistic Systems for Treating Inflammatory Bowel Disease through Peripheral Nerve Stimulation and AI-Powered Personalized Medicine

Publication ID: 24-11857778_0003_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Systems for Treating Inflammatory Bowel Disease through Peripheral Nerve Stimulation and AI-Powered Personalized Medicine,” Published Technical Disclosure No. 24-11857778_0003_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857778_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,778.

Summary of the Inventive Concept

This inventive concept integrates peripheral nerve stimulation with AI, IoT, and blockchain technologies to create a personalized treatment system for inflammatory bowel disease, offering improved treatment outcomes and enhanced patient care.

Background and Problem Solved

The original patent disclosed a method for treating inflammatory bowel disease through peripheral nerve stimulation. However, it lacked the capability to provide personalized treatment recommendations, secure patient data management, and real-time monitoring of treatment response. The new inventive concept addresses these limitations by combining peripheral nerve stimulation with AI-powered diagnostic capabilities, IoT-enabled sensors, and blockchain-based patient data management.

Detailed Description of the Inventive Concept

The synergistic system consists of a peripheral nerve stimulation module, an AI-powered diagnostic module, and a blockchain-based patient data management system. The AI-powered diagnostic module analyzes the patient's medical history and provides personalized treatment recommendations. The peripheral nerve stimulation module delivers targeted electrical stimulation to the patient's peripheral nerves based on the AI-recommended treatment plan. The blockchain-based patient data management system securely stores and updates the patient's treatment records, ensuring data integrity and confidentiality. The system also incorporates IoT-enabled sensors to monitor the patient's vital signs and treatment response, transmitting the data to a cloud-based server for analysis and feedback.

Novelty and Inventive Step

The new inventive concept is novel and non-obvious in its combination of peripheral nerve stimulation with AI-powered diagnostics, IoT-enabled sensors, and blockchain-based patient data management. The integration of these distinct technologies enables personalized treatment recommendations, real-time monitoring, and secure data management, which are not possible with the original patent's method.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different AI algorithms, various IoT sensor configurations, or alternative blockchain-based data management systems. Additionally, the system could be adapted for treating other inflammatory diseases or expanded to include additional diagnostic modalities.

Potential Commercial Applications and Market

The synergistic system has significant commercial potential in the healthcare industry, particularly in the treatment of inflammatory bowel disease. The system's ability to provide personalized treatment recommendations, real-time monitoring, and secure data management addresses a significant unmet need in the market. The target industries include pharmaceutical companies, medical device manufacturers, and healthcare providers.

Original Patent Information

Patent NumberUS 11,857,778
TitleSystems and methods for treating inflammatory bowel disease through peripheral nerve stimulation
Assignee(s)Cala Health, Inc.