TTField-based Neurological Disorder Treatment Systems

Publication ID: 24-11857782_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “TTField-based Neurological Disorder Treatment Systems,” Published Technical Disclosure No. 24-11857782_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857782_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,782.

Summary of the Inventive Concept

The inventive concept disclosed herein relates to novel applications of Tumor Treating Fields (TTFields) technology in veterinary medicine, stroke rehabilitation, ADHD treatment, chronic pain management, and Parkinson's disease treatment, utilizing implantable transducer arrays and real-time monitoring to deliver targeted TTFields therapy.

Background and Problem Solved

The original Optune system, as described in the original patent, is limited to treating human tumors. However, the core technology of TTFields has the potential to be applied to various other medical fields. The new inventive concept addresses the problem of limited TTFields applications by expanding its use to treat neurological disorders in veterinary medicine, rehabilitate stroke victims, enhance cognitive function in individuals with ADHD, treat chronic pain in amputees, and improve motor function in individuals with Parkinson's disease.

Detailed Description of the Inventive Concept

The inventive concept comprises implantable transducer arrays, configured to deliver TTFields to specific target regions in the brain or spinal cord, and controllers or wearable devices that adjust the TTFields in response to real-time data from the patient. The transducer arrays are designed for implantation within the patient's body, and the controllers or wearable devices monitor and adjust the TTFields to ensure optimal treatment. In veterinary medicine, the system is adapted for treating neurological disorders in animals. For stroke rehabilitation, the method involves implanting a transducer array in the affected region and monitoring motor function recovery. In ADHD treatment, the system targets the prefrontal cortex, and in chronic pain management, the system is adapted for treating residual limb pain in amputees. For Parkinson's disease treatment, the system targets the basal ganglia.

Novelty and Inventive Step

The new claims introduce novel applications of TTFields technology, expanding its use beyond tumor treatment to address various neurological disorders. The inventive step lies in the adaptation of the core technology to these new fields, incorporating real-time monitoring and adjustment of TTFields to ensure effective treatment.

Alternative Embodiments and Variations

Alternative embodiments may include varying the design and placement of the transducer arrays, using different types of sensors or monitoring devices, or incorporating additional features such as AI-powered optimization of TTFields delivery. Variations may also include adapting the system for treating other neurological disorders or conditions.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the veterinary medicine, neurology, and medical device industries. The target market includes veterinary clinics, hospitals, and medical research institutions, as well as companies developing treatments for neurological disorders.

Original Patent Information

Patent NumberUS 11,857,782
TitleDelivering tumor treating fields (TTFields) using implantable transducer arrays
Assignee(s)Novocure GmbH