Synergistic Gastrointestinal Therapeutic Systems

Publication ID: 24-11857783_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Gastrointestinal Therapeutic Systems,” Published Technical Disclosure No. 24-11857783_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857783_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,783.

Summary of the Inventive Concept

A novel, integrated system combining implantable and non-invasive stimulators with AI, IoT, blockchain, and advanced materials for personalized, data-driven gastrointestinal therapeutics.

Background and Problem Solved

The original patent addressed gastrointestinal therapeutics through implantable and non-invasive stimulators. However, these systems lacked real-time data analysis, secure data storage, and personalized treatment planning. The new inventive concept integrates distinct technologies to create a more powerful, synergistic system that addresses these limitations.

Detailed Description of the Inventive Concept

The system comprises a miniaturized implant or non-invasive stimulator integrated with AI-powered diagnostic modules for real-time analysis of GI tract activities. IoT sensors enable real-time monitoring of patient physiological signals, while blockchain-based data storage ensures secure patient data management. The system also incorporates novel biocompatible materials, data analytics modules, and AI-driven predictive analytics for personalized treatment planning. The wearable device tracks gut-brain axis activities, and a mobile app enables patient engagement and data tracking.

Novelty and Inventive Step

The new claims introduce the integration of AI, IoT, blockchain, and advanced materials with implantable and non-invasive stimulators, providing a synergistic system that offers real-time data analysis, secure data storage, and personalized treatment planning. This integration is new and non-obvious compared to the original patent.

Alternative Embodiments and Variations

Alternative embodiments may include varying the type of AI algorithm used, incorporating different IoT sensors, or utilizing alternative blockchain-based data storage solutions. Variations may also include integrating the system with other healthcare technologies, such as telemedicine platforms or electronic health records.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the gastrointestinal therapeutics market, with applications in treating gastrointestinal dysmotility, obesity, and other related disorders. The system's data-driven approach and personalized treatment planning capabilities position it for success in the growing digital health market.

Field of Art

Biomedical engineering, specifically gastrointestinal stimulation technologies, focusing on electrical neurostimulation systems for therapeutic interventions

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device researcher with expertise in electrical stimulation, neural interface technologies, signal processing, and medical device integration, holding advanced degrees in bioengineering or related fields

Obviousness Rationale

A PHOSITA would recognize that integrating AI, IoT, and blockchain technologies with existing electrical stimulation systems represents a predictable technological evolution. The source patent's foundational work on transcutaneous and implantable stimulators provides a clear technical framework for extending functionality through digital technologies. The proposed variations leverage known computational and communication technologies to enhance the core stimulation methodology described in the original patent.

Obvious Combinations & Variations

Source Patent Element
Stimulator with independently addressable electrodes for transcutaneous stimulation
PTD Variation
Adding AI-powered diagnostic module for real-time analysis of GI tract activities
Obviousness Reasoning
Integrating computational analysis with electrical stimulation is a known technique in medical device design, representing a predictable application of machine learning to existing stimulation technologies
Source Patent Element
Mobile device for controlling stimulator and receiving physiological signals
PTD Variation
Blockchain-based secure data storage and IoT sensor integration
Obviousness Reasoning
Enhancing data management and communication protocols is an obvious extension of existing mobile device interfaces, utilizing standard cybersecurity and networking technologies
Source Patent Element
Electrical field directed through spinal ganglions for neural modulation
PTD Variation
AI-driven predictive analytics for identifying optimal stimulation parameters
Obviousness Reasoning
Algorithmic optimization of stimulation parameters is a logical progression in neural interface technologies, representing a finite set of predictable computational approaches
Source Patent Element
Transcutaneous and implantable stimulation systems for gastrointestinal therapeutics
PTD Variation
Wearable device tracking gut-brain axis activities with personalized treatment planning
Obviousness Reasoning
Expanding physiological monitoring capabilities is a natural design evolution in medical device technologies, utilizing standard sensor and data processing techniques
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857783, a person having ordinary skill in the art would find the proposed variations in gastrointestinal stimulation technologies obvious and predictable extensions of existing electrical neurostimulation methodologies. The integration of AI, IoT, and blockchain technologies represents a straightforward technological progression that would be apparent to a skilled practitioner, thereby rendering potential patent claims in this domain obvious and unpatentable.

Original Patent Information

Patent NumberUS 11,857,783
TitleImplantable and non-invasive stimulators for gastrointestinal therapeutics
Assignee(s)The Regents of the University of California