Enhanced Methods and Apparatuses for Reducing Bleeding via Coordinated Trigeminal and Vagal Nerve Stimulation

Publication ID: 24-11857788_0001_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Methods and Apparatuses for Reducing Bleeding via Coordinated Trigeminal and Vagal Nerve Stimulation,” Published Technical Disclosure No. 24-11857788_0001_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857788_0001_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,788.

Summary of the Inventive Concept

Improved systems and methods for reducing bleeding in patients by simultaneously stimulating the trigeminal and vagal nerves, incorporating real-time feedback mechanisms and advanced sensor technologies to enhance treatment efficacy and safety.

Background and Problem Solved

The original patent disclosed methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation. However, the existing patent had limitations in terms of adjusting stimulation intensity in real-time, remote monitoring, and power source lifespan. The new inventive concept addresses these limitations by introducing advanced sensor technologies, real-time feedback mechanisms, and miniaturized stimulators with extended power sources.

Detailed Description of the Inventive Concept

The enhanced system for reducing bleeding in patients comprises a neural stimulator configured to simultaneously stimulate the trigeminal and vagal nerves, and a sensor for detecting blood coagulation levels. The neural stimulator adjusts the stimulation intensity based on the detected blood coagulation levels, ensuring optimal treatment efficacy. Additionally, the system includes a wearable device and a mobile application for remotely monitoring and adjusting the stimulation intensity. The neural stimulation device features a miniaturized stimulator and an extended lifespan power source, enhancing user convenience and reducing maintenance requirements.

Novelty and Inventive Step

The new claims introduce the concept of real-time feedback mechanisms, advanced sensor technologies, and miniaturized stimulators with extended power sources, which are not present in the original patent. These advancements provide a significant improvement in treatment efficacy, safety, and user convenience, thereby constituting a novel and non-obvious inventive step.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept may include the use of different sensor technologies, such as optical or acoustic sensors, to detect blood coagulation levels. Additionally, the system could be adapted for use in various medical procedures, such as surgical interventions or trauma care, or integrated with other medical devices, such as patient monitoring systems.

Potential Commercial Applications and Market

The enhanced system for reducing bleeding in patients has significant commercial potential in the medical device industry, particularly in the areas of surgical interventions, trauma care, and patient monitoring. The target market includes hospitals, clinics, and medical research institutions, with potential for expansion into the consumer market for personal health monitoring and emergency response applications.

Field of Art

Biomedical engineering, specifically neural stimulation technologies for hemostasis and bleeding control, involving electrical nerve stimulation techniques and medical device design

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device designer with expertise in neurostimulation, electrical medical devices, sensor integration, and physiological monitoring technologies, holding advanced degrees and practical experience in developing neural stimulation systems

Obviousness Rationale

A person having ordinary skill in the art would recognize that adding real-time feedback mechanisms, sensor technologies, and adaptive stimulation to the existing neural stimulation approach represents a predictable engineering solution for improving treatment precision and patient outcomes. The core concept of trigeminal and vagal nerve stimulation remains consistent, with the PTD introducing incremental technological enhancements that would be obvious to implement using standard medical device design principles. These variations represent logical extensions of the source patent's fundamental neural stimulation methodology.

Obvious Combinations & Variations

Source Patent Element
Non-invasive electrical stimulation system targeting trigeminal and vagal nerves
PTD Variation
Adding real-time blood coagulation sensor for dynamically adjusting stimulation intensity
Obviousness Reasoning
Integrating feedback sensors with neural stimulation is a known technique for improving treatment precision, representing a predictable application of closed-loop medical device design principles
Source Patent Element
Wearable apparatus for nerve stimulation
PTD Variation
Incorporating mobile application for remote monitoring and stimulation control
Obviousness Reasoning
Wireless connectivity and smartphone integration are standard design choices for modern medical devices, providing enhanced patient monitoring and convenience
Source Patent Element
Electrical nerve stimulation system
PTD Variation
Miniaturized stimulator with extended lifespan power source
Obviousness Reasoning
Technological miniaturization and improved power management are routine engineering improvements in medical device development, representing finite identified solutions for enhancing device usability
Source Patent Element
Periodic nerve stimulation for bleeding control
PTD Variation
Prophylactic stimulation protocol before surgical procedures
Obviousness Reasoning
Extending treatment protocols to preventative scenarios is an obvious clinical adaptation based on understanding the underlying physiological mechanisms
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857788, the present publication demonstrates that the claimed variations in neural stimulation technology for bleeding control would have been obvious to a person having ordinary skill in the art at the time of invention. The incremental technological enhancements, including real-time sensor integration, adaptive stimulation protocols, and improved device design, represent predictable engineering solutions that do not rise to the level of non-obvious innovation, thus rendering potential derivative claims obvious and unpatentable.

Original Patent Information

Patent NumberUS 11,857,788
TitleMethods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
Assignee(s)THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH