Synergistic Neurostimulation Systems for Enhanced Therapeutic Efficacy

The present inventive concept integrates advanced technologies, such as AI, IoT, blockchain, and new materials, with the original neurostimulation method and system to create a more powerful and adaptive system for active emulation of passive discharge in the presence of MRI/EMI interference.

The original patent application Ser. No. 16/401,971, titled 'NEUROSTIMULATION METHOD AND SYSTEM WITH CURRENT REGULATOR BIASED BY FLOATING POWER SUPPLY', relates to neurostimulation methods and systems. However, the existing neurostimulation systems lack the ability to adapt to individual patient needs, are vulnerable to interference, and have limited data security and analytics capabilities. The present inventive concept addresses these limitations by introducing synergistic combinations of distinct technologies to enhance therapeutic efficacy and patient outcomes.

The inventive concept comprises a neurostimulation system with a plurality of electrodes positioned within a patient, including an active electrode configured to be a cathode electrode located proximate to tissue of interest associated with a target region. The system integrates AI, IoT, blockchain, and new materials to enhance stimulation efficacy, adapt to individual patient needs, and ensure secure data storage and transmission. The AI module uses machine learning algorithms to analyze patient-specific data and predict optimal stimulation parameters, which are then delivered to the target region through the neurostimulation module. The IoT-enabled sensor array provides real-time feedback to adjust the stimulation parameters, while the blockchain-based data storage module securely stores and transmits patient-specific stimulation parameters. The nanomaterial-based coating on at least one of the electrodes enhances stimulation efficacy. The inventive concept enables personalized neurostimulation therapy with improved therapeutic outcomes and reduced side effects.

The present inventive concept is novel and non-obvious in its synergistic combination of AI, IoT, blockchain, and new materials with the original neurostimulation method and system. The integration of these distinct technologies enables adaptive, personalized, and secure neurostimulation therapy, which is not anticipated by the original patent or existing neurostimulation systems.

Alternative embodiments of the inventive concept may include variations in the AI module, such as using different machine learning algorithms or integrating with other AI systems. The IoT-enabled sensor array may be replaced with other sensing technologies, such as wearable devices or implantable sensors. The blockchain-based data storage module may be substituted with other secure data storage solutions, such as encrypted databases or cloud storage. The nanomaterial-based coating may be replaced with other advanced materials or coatings to enhance stimulation efficacy.

The present inventive concept has significant commercial potential in the neurostimulation market, which is projected to grow significantly in the coming years. The inventive concept's ability to provide personalized, adaptive, and secure neurostimulation therapy makes it an attractive solution for patients and healthcare providers. The market for neurostimulation systems is expected to expand as the technology advances and becomes more widely adopted.