Adaptive Neurostimulation System for Real-time MRI/EMI Interference Mitigation

Publication ID: 24-11857789_0010_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Adaptive Neurostimulation System for Real-time MRI/EMI Interference Mitigation,” Published Technical Disclosure No. 24-11857789_0010_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857789_0010_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,789.

Summary of the Inventive Concept

An advanced neurostimulation system that dynamically adjusts stimulation parameters in response to real-time MRI/EMI interference detection, ensuring optimal therapy delivery and patient safety.

Background and Problem Solved

The original patent addresses the challenge of regulating current to provide active emulation of passive discharge in the presence of MRI/EMI interference. However, it relies on fixed stimulation parameters, which may not be effective in mitigating interference in dynamic environments. The new inventive concept solves this problem by introducing adaptive stimulation parameters that respond to real-time interference detection.

Detailed Description of the Inventive Concept

The adaptive neurostimulation system comprises a plurality of electrodes, including an active electrode and an anode electrode, positioned within a patient. The system detects MRI/EMI interference in real-time using a sensor and adjusts stimulation parameters of the active electrode accordingly. This is achieved through a neural network trained to predict optimal stimulation parameters based on historical interference patterns. The regulator circuit adjusts the stimulation parameters in real-time based on the predicted optimal parameters, ensuring optimal neurostimulation therapy delivery. The system can also incorporate a controller that adjusts stimulation parameters based on detected changes in a patient's neural activity in response to MRI/EMI interference.

Novelty and Inventive Step

The new inventive concept introduces a paradigm shift in neurostimulation technology by incorporating real-time interference detection and adaptive stimulation parameters. This is a significant departure from the original patent, which relies on fixed stimulation parameters. The use of a neural network to predict optimal stimulation parameters and the regulator circuit's real-time adjustments are novel and non-obvious features that provide a significant improvement over existing technologies.

Alternative Embodiments and Variations

Alternative embodiments of the adaptive neurostimulation system could include using different types of sensors or neural networks to detect MRI/EMI interference. Additionally, the system could be integrated with other medical devices, such as MRI machines, to provide real-time feedback and optimization. Variations of the system could also be designed for specific medical applications, such as deep brain stimulation or spinal cord stimulation.

Potential Commercial Applications and Market

The adaptive neurostimulation system has significant commercial potential in the medical device industry, particularly in the areas of neurology, neurosurgery, and psychiatry. The system's ability to provide optimal neurostimulation therapy in dynamic environments could lead to improved patient outcomes and reduced healthcare costs. The market for this technology is expected to grow as the demand for advanced neurostimulation systems increases.

Field of Art

Biomedical engineering, specifically neurostimulation systems and electromagnetic interference mitigation in medical implantable devices. Requires advanced understanding of electrical engineering, signal processing, neural interface technologies, and medical device design

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer with advanced degree (MS/PhD), expertise in neural stimulation circuits, signal processing algorithms, and medical device design, familiar with adaptive control systems and interference mitigation techniques

Obviousness Rationale

A PHOSITA would recognize that the PTD's adaptive neurostimulation approach represents a predictable extension of the source patent's interference detection methodology. The core technical problem of managing electromagnetic interference in neural stimulation remains consistent, with the PTD introducing incremental improvements in real-time parameter adjustment using well-established machine learning and control system principles. The neural network and adaptive parameter modification are logical technological progressions that would be apparent to a skilled practitioner seeking to enhance neurostimulation reliability.

Obvious Combinations & Variations

Source Patent Element
EMI antenna configured to generate interference feedback signal
PTD Variation
Neural network trained to predict optimal stimulation parameters based on historical interference patterns
Obviousness Reasoning
Predictable application of machine learning to existing interference detection technique, representing an obvious design optimization for managing complex electromagnetic interactions
Source Patent Element
Regulator circuit with error amplifier for managing electrode current
PTD Variation
Real-time stimulation parameter adjustment based on detected neural activity changes
Obviousness Reasoning
Known technique of dynamic circuit adaptation, applying feedback control principles to improve neurostimulation precision
Source Patent Element
Active and anode electrodes with configurable stimulation parameters
PTD Variation
Personalized stimulation profile generation using historical interference and neural activity data
Obviousness Reasoning
Obvious extension of existing personalization techniques in medical device design, leveraging patient-specific data for improved therapeutic outcomes
Source Patent Element
Current regulation mechanism for managing electrode discharge
PTD Variation
Sensor-based real-time interference detection and parameter modification
Obviousness Reasoning
Predictable implementation of adaptive control principles, representing a standard engineering approach to managing dynamic system interactions
Source Patent Element
Electromagnetic interference mitigation in neurostimulation system
PTD Variation
Integration with external medical devices like MRI machines for coordinated interference management
Obviousness Reasoning
Logical system integration approach, representing an obvious solution to cross-device electromagnetic compatibility challenges
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857789 and the published technical disclosure, a person having ordinary skill in the art would find the claimed adaptive neurostimulation system variations obvious and anticipated. The incremental technological improvements represent predictable applications of known signal processing, machine learning, and adaptive control techniques to the existing neurostimulation interference mitigation framework, thereby rendering such variations unpatentable under 35 U.S.C. Section 103.

Original Patent Information

Patent NumberUS 11,857,789
TitleNeurostimulation method and system for active emulation of passive discharge in presence of MRI/EMI interference
Assignee(s)Advanced Neuromodulation Systems, Inc.