Neural Modulation 2.0: Multi-Modal Energy Delivery and Adaptive Feedback Control

Publication ID: 24-11857791_0005_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Neural Modulation 2.0: Multi-Modal Energy Delivery and Adaptive Feedback Control,” Published Technical Disclosure No. 24-11857791_0005_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857791_0005_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,791.

Summary of the Inventive Concept

A next-generation neural modulation system that combines multi-modal energy delivery with adaptive feedback control, enabling more precise and effective treatment of various physiological conditions and disorders.

Background and Problem Solved

The original Arced Implant Unit for Modulation of Nerves patent has limitations in terms of energy delivery and nerve damage prevention. The new inventive concept addresses these limitations by introducing a multi-modal energy delivery module and an adaptive feedback control system, allowing for real-time monitoring and adjustment of energy delivery to prevent potential nerve damage.

Detailed Description of the Inventive Concept

The Neural Modulation 2.0 system comprises a multi-modal energy delivery module capable of simultaneously delivering electrical, thermal, and optical energy to a nerve. This module is combined with an adaptive feedback control system that utilizes real-time neural activity monitoring to adjust the energy delivery. The system also includes machine learning algorithms to predict and prevent potential nerve damage during modulation. Additionally, the system features a flexible, self-expanding lattice structure that conforms to the shape of the nerve, ensuring optimal energy delivery and minimizing nerve damage risk.

Novelty and Inventive Step

The new inventive concept's multi-modal energy delivery module and adaptive feedback control system represent a significant departure from the original patent's single-mode energy delivery approach. The integration of machine learning algorithms and real-time neural activity monitoring further enhances the system's precision and safety.

Alternative Embodiments and Variations

Alternative embodiments of the Neural Modulation 2.0 system could include variations in the type and combination of energy modalities, different lattice structure designs, or the incorporation of additional sensors and algorithms to further refine the system's performance.

Potential Commercial Applications and Market

The Neural Modulation 2.0 system has significant commercial potential in the treatment of various physiological conditions and disorders, including sleep breathing disorders, chronic pain, and neurological disorders. The system's advanced features and precision make it an attractive solution for patients and healthcare providers seeking more effective and safe treatment options.

Field of Art

Biomedical engineering, specifically neural modulation devices and methods for nerve stimulation and treatment of physiological conditions

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device designer with expertise in neural interfaces, electrical stimulation technologies, and implantable medical devices, holding advanced degrees in bioengineering or related fields

Obviousness Rationale

A person of ordinary skill would recognize that expanding the single-mode energy delivery of the source patent to multi-modal energy delivery is a predictable extension of existing neural modulation technologies. The integration of machine learning and adaptive feedback represents a natural progression in medical device design, leveraging known computational techniques to improve precision and safety of neural stimulation approaches.

Obvious Combinations & Variations

Source Patent Element
Implantable electrical modulator with flexible carrier unit for nerve stimulation
PTD Variation
Multi-modal energy delivery module combining electrical, thermal, and optical energy
Obviousness Reasoning
Expanding energy delivery modes is a predictable design optimization for neural modulation, with multiple energy types known to be effective for nerve interaction in medical literature
Source Patent Element
Arced implant unit with flexible carrier conforming to nerve shape
PTD Variation
Self-expanding lattice structure with real-time adaptive conforming capabilities
Obviousness Reasoning
Improving device flexibility and responsiveness is an obvious engineering solution to enhance patient-specific nerve modulation, representing a straightforward technological progression
Source Patent Element
Nerve stimulation for specific physiological conditions
PTD Variation
Machine learning algorithms for predicting and preventing nerve damage during modulation
Obviousness Reasoning
Incorporating computational intelligence to improve medical device safety is a well-established trend in biomedical engineering, representing a logical and predictable technological advancement
Source Patent Element
Implant unit with multiple electrode pairs for nerve modulation
PTD Variation
Adaptive feedback control system with real-time neural activity monitoring
Obviousness Reasoning
Enhancing electrode functionality through dynamic monitoring is a natural extension of existing neural interface technologies, representing an obvious improvement to stimulation precision
Source Patent Element
Nerve stimulation for specific physiological conditions
PTD Variation
Personalized neural modulation therapy using artificial intelligence and patient-specific data
Obviousness Reasoning
Tailoring medical treatments using patient-specific computational analysis is a predictable and well-established approach in modern medical device design
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857791 and the disclosed variations, a person of ordinary skill in the art would find the claimed neural modulation system variations obvious and anticipated. The progressive technological extensions, including multi-modal energy delivery, adaptive feedback, and machine learning integration, represent predictable advancements within the established technological domain of neural stimulation devices.

Original Patent Information

Patent NumberUS 11,857,791
TitleArced implant unit for modulation of nerves
Assignee(s)Nyxoah SA