Synergistic Cranial Nerve Stimulation Systems

Publication ID: 24-11857792_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Cranial Nerve Stimulation Systems,” Published Technical Disclosure No. 24-11857792_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857792_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,792.

Summary of the Inventive Concept

A novel, integrated system that combines cranial nerve stimulation with AI, IoT, blockchain, and advanced materials to treat various disorders and diseases, enhancing patient outcomes and quality of life.

Background and Problem Solved

The original patent, 'Methods for stimulation of cranial nerves', addressed the need for effective treatments for sleep disorders, breathing disorders, and other conditions. However, it had limitations in terms of personalized therapy, data security, and device integration. The new inventive concept addresses these limitations by integrating cranial nerve stimulation with distinct technologies, creating a more powerful system.

Detailed Description of the Inventive Concept

The synergistic system comprises a neuromodulation device, configured to apply electrical stimulation to a cranial nerve target, integrated with one or more of the following: an AI module for personalized therapy, an IoT network for remote monitoring and data transmission, a blockchain-based data storage system for secure patient data management, and novel biomaterials for enhanced tissue integration. The system enables real-time analysis of patient physiologic data, prediction of disease risk, and prevention of disease onset.

Novelty and Inventive Step

The new claims introduce novel combinations of cranial nerve stimulation with AI, IoT, blockchain, and advanced materials, providing a synergistic effect that enhances the original patent's functionality and value. The inventive step lies in the integration of these distinct technologies to create a more powerful, personalized, and secure system for treating various disorders and diseases.

Alternative Embodiments and Variations

Alternative embodiments may include variations in the AI module's algorithm, the IoT network's architecture, the blockchain-based data storage system's implementation, and the novel biomaterials' composition. Additionally, the system could be adapted for use in other therapeutic areas, such as pain management, depression, or epilepsy.

Potential Commercial Applications and Market

The synergistic cranial nerve stimulation system has significant commercial potential in the healthcare industry, particularly in the areas of sleep disorders, respiratory disorders, and chronic pain management. The system's ability to provide personalized therapy, secure data management, and real-time monitoring makes it an attractive solution for patients, clinicians, and healthcare providers.

Field of Art

Biomedical engineering, specifically neuromodulation devices for cranial nerve stimulation and treatment of neurological disorders

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device researcher with expertise in neural stimulation technologies, electrical engineering, and medical device design, familiar with emerging technologies in personalized medical interventions

Obviousness Rationale

A person of ordinary skill would recognize that integrating AI, IoT, and advanced data management technologies with existing neuromodulation devices represents a predictable extension of current medical device development. The source patent establishes a foundational method for cranial nerve stimulation, which naturally invites technological enhancements to improve patient monitoring, personalization, and treatment efficacy. These technological integrations represent incremental improvements that would be obvious to a skilled practitioner seeking to optimize neural stimulation therapies.

Obvious Combinations & Variations

Source Patent Element
Implantable neuromodulation device for stimulating cranial nerves to treat sleep disorders
PTD Variation
Adding an AI module to dynamically adjust stimulation parameters based on patient sleep patterns
Obviousness Reasoning
Adaptive medical device technologies are well-known, and applying machine learning to optimize neural stimulation represents a predictable application of known techniques to improve treatment precision
Source Patent Element
Electrical stimulation of hypoglossal nerve for treating obstructive sleep apnea
PTD Variation
Incorporating IoT network connectivity for remote monitoring and data transmission
Obviousness Reasoning
Remote patient monitoring is a standard approach in medical device design, and integrating wireless communication with existing neural stimulation devices would be an obvious enhancement for a skilled practitioner
Source Patent Element
Implantable device positioned in anterior cervical region between mylohyoid and digastric muscles
PTD Variation
Utilizing novel biomaterials to improve tissue integration and reduce device migration
Obviousness Reasoning
Material science improvements for medical implants are a routine area of research, and developing enhanced biomaterials to address known device limitations represents an obvious design optimization
Source Patent Element
Neuromodulation targeting multiple cranial nerves including hypoglossal, trigeminal, and vagus nerves
PTD Variation
Implementing blockchain-based secure data storage for patient treatment records
Obviousness Reasoning
Secure data management is a critical concern in medical technologies, and applying blockchain to medical device data tracking represents a straightforward technological integration
Source Patent Element
Method for treating various neurological and respiratory disorders through cranial nerve stimulation
PTD Variation
Adding machine learning algorithms to predict disease risk and prevent onset
Obviousness Reasoning
Predictive analytics in medical technologies are an established approach, and applying machine learning to analyze physiological data from neural stimulation devices is a predictable technological progression
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857792 and the published technical disclosure, a person of ordinary skill in the art would find the claimed variations obvious, as they represent predictable combinations of known medical device technologies with standard approaches to improving neural stimulation therapies through data integration, adaptive algorithms, and advanced materials.

Original Patent Information

Patent NumberUS 11,857,792
TitleMethods for stimulation of cranial nerves
Assignee(s)NuXcel2, L.L.C.