Adaptive Cardiac Sensing and Therapy Based on Real-time Patient Data

Publication ID: 24-11857798_0006_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Adaptive Cardiac Sensing and Therapy Based on Real-time Patient Data,” Published Technical Disclosure No. 24-11857798_0006_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857798_0006_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,798.

Summary of the Inventive Concept

This inventive concept introduces an advanced cardiac sensing and therapy system that dynamically adjusts therapy parameters and electrode vectors based on real-time patient activity data, machine learning algorithms, and personalized therapy recommendations from a remote server.

Background and Problem Solved

The original patent disclosed a cardiac sensing and therapy system that delivered anti-tachyarrhythmia shock therapy based on a patient's heart position state. However, this system had limitations in adjusting therapy parameters in real-time and lacked personalized therapy recommendations. The new inventive concept addresses these limitations by incorporating real-time patient data, machine learning algorithms, and remote server analysis to optimize cardiac therapy delivery.

Detailed Description of the Inventive Concept

The new system comprises a processing circuitry that determines a patient's current heart position state and modifies cardiac therapy or sensing parameter values accordingly. The processing circuitry further adjusts the modified parameter values based on real-time patient activity data, such as respiratory phase, rate, or depth. Additionally, the system utilizes machine learning algorithms trained on historical patient data to optimize therapy delivery. In another embodiment, the system includes a communication module that transmits the patient's heart position state to a remote server, which analyzes the data and provides personalized therapy recommendations to the medical device system. The system can also store historical data of the patient's heart position states and corresponding therapy outcomes, allowing for adaptive adjustments to therapy delivery.

Novelty and Inventive Step

The new inventive concept introduces the use of real-time patient activity data, machine learning algorithms, and remote server analysis to optimize cardiac therapy delivery. These features are not present in the original patent and provide a significant improvement over existing cardiac sensing and therapy systems.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different types of sensors to detect patient activity, such as accelerometers or gyroscopes. The system could also be adapted for use in other medical applications, such as neurological or musculoskeletal therapy. Additionally, the remote server could be replaced with a local processing unit or a cloud-based service.

Potential Commercial Applications and Market

The adaptive cardiac sensing and therapy system has significant commercial potential in the medical device industry, particularly in the cardiac rhythm management market. The system's ability to provide personalized and optimized therapy delivery could improve patient outcomes and reduce healthcare costs. The market for this technology could include hospitals, clinics, and medical device manufacturers.

Field of Art

Medical device systems, specifically cardiac sensing and therapy delivery technologies involving implantable medical devices (IMDs), electrode configuration, and physiological state monitoring

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer with expertise in cardiac medical device design, signal processing, electrical engineering, and advanced sensor integration, holding at least a master's degree with 3-5 years of experience in medical device development

Obviousness Rationale

A PHOSITA would recognize that the PTD's proposed variations represent predictable extensions of the source patent's core teachings about adaptive cardiac therapy delivery. The machine learning and real-time data integration techniques are logical next-generation improvements to existing cardiac sensing methodologies. The proposed system builds upon the foundational concepts of position-based therapy modification by introducing additional data processing and personalization strategies.

Obvious Combinations & Variations

Source Patent Element
Method for modifying anti-tachyarrhythmia shock therapy based on patient heart position state
PTD Variation
Adding machine learning algorithms to dynamically adjust therapy parameters based on historical patient data
Obviousness Reasoning
Applying machine learning to medical device parameter optimization is a known technique, representing a predictable application of computational intelligence to existing adaptive therapy systems
Source Patent Element
Electrode-based cardiac sensing with posture-dependent modifications
PTD Variation
Introducing remote server analysis and personalized therapy recommendation transmission
Obviousness Reasoning
Integrating cloud-based or remote diagnostic support is a standard evolution in medical device technology, representing an obvious enhancement to existing sensing methodologies
Source Patent Element
Cardiac therapy delivery system with multiple electrode configurations
PTD Variation
Dynamically modifying electrode vectors using real-time electrogram data
Obviousness Reasoning
Adaptive electrode vector selection based on physiological signals is a logical extension of existing multi-electrode medical device design principles
Source Patent Element
Patient position and respiratory state detection for therapy modification
PTD Variation
Incorporating additional sensor types like accelerometers and gyroscopes for activity tracking
Obviousness Reasoning
Expanding sensor modalities to capture patient state is a routine design optimization approach in medical device engineering
Source Patent Element
Cardiac sensing method with parameter adjustment based on physiological state
PTD Variation
Implementing feedback control algorithms that store and learn from historical therapy outcomes
Obviousness Reasoning
Developing adaptive learning systems that improve performance through historical data analysis represents a predictable technological progression
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857798 and the disclosed variations, a person of ordinary skill in the art would find the proposed cardiac sensing and therapy delivery system obvious and anticipated, as the technical modifications represent straightforward extensions of existing medical device design principles involving adaptive parameter modification, machine learning integration, and personalized therapy optimization.

Original Patent Information

Patent NumberUS 11,857,798
TitleModification of cardiac sensing and therapy
Assignee(s)Medtronic, Inc.