Enhanced Alpha-Emitter Radiation Therapy with Controlled Radon Release and Real-Time Beta Radiation Supplement

Publication ID: 24-11857803_0001_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Alpha-Emitter Radiation Therapy with Controlled Radon Release and Real-Time Beta Radiation Supplement,” Published Technical Disclosure No. 24-11857803_0001_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857803_0001_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,803.

Summary of the Inventive Concept

A novel radiation therapy system that combines alpha-emitter radiation with controlled radon release and real-time beta radiation supplement, providing a more efficient and personalized treatment for cancer patients.

Background and Problem Solved

The original patent disclosed an interstitial source with combined alpha and non-alpha radiation for cancer treatment. However, it had limitations in controlling radon release and optimizing beta radiation. The new inventive concept addresses these limitations by introducing a controlled desorption probability of radon release and a real-time beta radiation supplement module, ensuring a more efficient and safe treatment.

Detailed Description of the Inventive Concept

The system comprises a radiation source with a controlled desorption probability of radon release, which is achieved through a specialized coating. The radiation source is paired with a beta radiation supplement module that can be adjusted in real-time to optimize the treatment. The system also includes a real-time radiation monitoring module to ensure safe and effective treatment. The radiation source can be personalized for individual patients based on their tumor characteristics, providing a more targeted treatment.

Novelty and Inventive Step

The new inventive concept introduces the controlled desorption probability of radon release, which is a significant improvement over the original patent. The real-time beta radiation supplement module and the personalization feature based on tumor characteristics are also novel and non-obvious aspects of the invention.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include different types of radiation sources, such as seeds or wires, and various methods for controlling radon release. The system could also be adapted for use in different types of cancer treatment, such as external beam radiation therapy.

Potential Commercial Applications and Market

The enhanced alpha-emitter radiation therapy system has significant commercial potential in the cancer treatment market, particularly in the area of personalized medicine. The system's ability to provide real-time monitoring and adjustment of beta radiation could lead to improved treatment outcomes and increased patient safety, making it an attractive option for hospitals and cancer treatment centers.

Original Patent Information

Patent NumberUS 11,857,803
TitleDiffusing alpha-emitter radiation therapy with enhanced beta treatment
Assignee(s)Alpha Tau Medical Ltd