Adaptive Radiation Therapy for Niche Environments

Publication ID: 24-11857803_0009_PTD
Published: October 28, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Adaptive Radiation Therapy for Niche Environments,” Published Technical Disclosure No. 24-11857803_0009_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857803_0009_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,803.

Summary of the Inventive Concept

A system for providing implantable radiation sources with combined alpha and non-alpha radiation, tailored to specific, challenging operational environments, such as high-altitude, disaster-stricken, high-security, extreme weather, or limited medical infrastructure areas.

Background and Problem Solved

The original patent disclosed a radiotherapy apparatus with combined alpha and non-alpha radiation. However, it did not address the unique challenges of specific environments, such as high-altitude, disaster-stricken, high-security, extreme weather, or limited medical infrastructure areas. The new inventive concept adapts the original patent's technology to these niche environments, ensuring effective and safe radiation therapy in diverse settings.

Detailed Description of the Inventive Concept

The inventive concept comprises a range of specialized radiation therapy systems and methods, each tailored to a specific niche environment. For high-altitude environments, the system features a support adapted for insertion into a body of a subject at high elevations, with radionuclide atoms of an alpha-emitting substance attached to the support, having a desorption probability of at least 1% but less than 30%. For disaster-stricken areas, the method involves implanting a radiotherapy source carrying alpha emitting atoms with a desorption probability of at least 1% but less than 30%, and providing supplemental beta radiation to the tumor site. The radiation therapy apparatus for high-security facilities features a sealed enclosure containing a radiotherapy source carrying alpha emitting atoms with a desorption probability of at least 1% but less than 30%, and a security mechanism preventing unauthorized access to the sealed enclosure. The portable radiation therapy system for extreme weather conditions includes a weather-resistant housing containing a radiotherapy source carrying alpha emitting atoms with a desorption probability of at least 1% but less than 30%, and a power source adapted to operate in extreme temperatures. Finally, the method for providing radiation therapy in areas with limited medical infrastructure involves deploying a pre-configured, self-contained radiation therapy unit carrying a radiotherapy source with alpha emitting atoms having a desorption probability of at least 1% but less than 30%, and remotely monitoring and controlling the radiation therapy unit.

Novelty and Inventive Step

The new inventive concept's novelty lies in its adaptation of the original patent's technology to specific, challenging operational environments, such as high-altitude, disaster-stricken, high-security, extreme weather, or limited medical infrastructure areas. The inventive step is the tailored design of each system and method to address the unique challenges of its respective environment, ensuring effective and safe radiation therapy in diverse settings.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include variations in the design of the support, radionuclide atoms, or security mechanisms, depending on the specific environment. For example, the system for high-altitude environments could be modified to accommodate different atmospheric pressures, while the apparatus for high-security facilities could incorporate additional safety features.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in various industries, including healthcare, disaster relief, and security. The market for radiation therapy systems and methods tailored to niche environments is substantial, with potential applications in remote or disaster-stricken areas, high-security facilities, and extreme weather conditions.

Original Patent Information

Patent NumberUS 11,857,803
TitleDiffusing alpha-emitter radiation therapy with enhanced beta treatment
Assignee(s)Alpha Tau Medical Ltd