Simulation-based drug treatment planning for specialized environments
Legal Citation
Summary of the Inventive Concept
A system and method for simulating and adjusting cavitation-enhanced drug-treatment procedures in high-security, disaster relief, extreme weather, high-altitude, and mobile medical unit environments, ensuring effective treatment outcomes in unique operational scenarios.
Background and Problem Solved
The original patent's simulation-based drug treatment planning system is limited in its applicability to conventional clinical settings. However, there is a growing need for adaptable solutions that can operate effectively in specialized environments, such as high-security facilities, disaster relief scenarios, extreme weather conditions, high-altitude locations, and mobile medical units. The new inventive concept addresses this limitation by introducing system and method adaptations that enable reliable and efficient treatment outcomes in these niche environments.
Detailed Description of the Inventive Concept
The new inventive concept comprises a system and method for simulating and adjusting cavitation-enhanced drug-treatment procedures in specialized environments. The system includes an ultrasound transducer, a processor, and memory storing a sonication parameter adapted for the specific environment. The method involves acquiring images of a patient's anatomy, identifying target tumor and BBB regions, and predicting tissue disruption as a function of time using a processor configured to account for the unique challenges of each environment. For instance, in high-security environments, the sonication parameter is adapted to minimize acoustic emission detectable by external surveillance systems. In disaster relief scenarios, the processor accounts for limited resources and infrastructure available. In extreme weather conditions, the sonication parameter is adapted to compensate for weather-related variations in ultrasound transmission. In high-altitude environments, the processor accounts for the effects of high altitude on ultrasound transmission and tissue properties. In mobile medical units, the sonication parameter is adapted to optimize treatment outcomes in a mobile medical unit with limited space and resources.
Novelty and Inventive Step
The new inventive concept introduces novel adaptations of the original system and method to address the specific challenges of high-security, disaster relief, extreme weather, high-altitude, and mobile medical unit environments. The inventive step lies in the development of environment-specific sonication parameters and processor configurations that enable effective treatment outcomes in these niche environments.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept may include additional sensors or imaging modalities to enhance treatment planning, or integration with other medical devices to expand the system's capabilities. Variations may include adapting the system for use in other specialized environments, such as space exploration or remote wilderness areas.
Potential Commercial Applications and Market
The new inventive concept has significant commercial potential in various industries, including healthcare, disaster relief, and defense. The system and method can be marketed as specialized solutions for high-security facilities, disaster relief organizations, extreme weather research institutions, high-altitude medical centers, and mobile medical units, providing a competitive edge in these niche markets.
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Medical imaging, ultrasound-based drug delivery systems, and neurological treatment technologies, requiring advanced knowledge of medical physics, signal processing, and biomedical engineering
Person of Ordinary Skill (PHOSITA) Profile
A biomedical engineer or medical device researcher with expertise in ultrasound technologies, blood-brain barrier manipulation, and computational modeling of medical interventions, holding advanced degrees and practical experience in translational medical technologies
Obviousness Rationale
A PHOSITA would recognize that the source patent's fundamental method of simulation-based BBB drug treatment can be readily adapted to various environmental contexts by modifying sonication parameters and computational approaches. The core technological framework remains consistent, with environmental adaptations representing predictable variations that a skilled practitioner would naturally explore to expand treatment applicability. The disclosed variations represent logical extensions of the original patent's core technological principles, achievable through routine engineering modifications.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,807 |
|---|---|
| Title | Simulation-based drug treatment planning |
| Assignee(s) | INSIGHTEC, LTD. |