Sonogenic Stimulation for Diverse Applications
Legal Citation
Summary of the Inventive Concept
Expanding the core technology of sonogenic stimulation to treat cancer, enhance athletic performance, monitor cardiac activity, treat neurological disorders, and rejuvenate skin, by applying ultrasound energy to targeted cells expressing TRP-4 polypeptide.
Background and Problem Solved
The original patent, 'Sonogenic stimulation of cells', focused on altering the function or activity of neurons in a mammalian subject. However, this invention is limited to neural applications. The new inventive concept addresses the need for a broader range of applications, leveraging the core technology to tackle diverse challenges in cancer treatment, athletic performance, cardiac monitoring, neurological disorders, and skin rejuvenation.
Detailed Description of the Inventive Concept
The new inventive concept comprises a sonogenic stimulation device configured to apply ultrasound energy to targeted cells expressing TRP-4 polypeptide. In cancer treatment, the device induces apoptosis in tumor cells. For athletic performance, it enhances muscle contraction force by stimulating muscle cells. In cardiac monitoring, it generates an electrical signal indicative of cardiac activity. For neurological disorders, it modulates neural activity. Finally, in skin rejuvenation, it increases collagen production in skin cells. The TRP-4 polypeptide is a crucial component, as it is activated by ultrasound energy to produce the desired effects.
Novelty and Inventive Step
The new inventive concept is novel and non-obvious because it applies the core technology of sonogenic stimulation to entirely new fields and use cases, which were not considered in the original patent. The inventive step lies in the recognition of the potential for sonogenic stimulation to address diverse challenges beyond neural applications.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include varying the type of cells targeted, the specific TRP polypeptide used, or the frequency and intensity of the ultrasound energy. Additionally, the device could be designed for implantation, wearable use, or handheld application.
Potential Commercial Applications and Market
The new inventive concept has significant commercial potential in the fields of oncology, sports medicine, cardiology, neurology, and cosmetics. The market for such applications is substantial, with potential customers including hospitals, clinics, research institutions, and individual consumers.
Original Patent Information
| Patent Number | US 11,857,809 |
|---|---|
| Title | Sonogenic stimulation of cells |
| Assignee(s) | Salk Institute for Biological Studies |