Enhanced Neural Activity Detection and Suppression System using Synergistic Combinations

Publication ID: 24-11857811_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Enhanced Neural Activity Detection and Suppression System using Synergistic Combinations,” Published Technical Disclosure No. 24-11857811_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857811_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,811.

Summary of the Inventive Concept

The present inventive concept integrates acoustic waves and/or ultrasound with distinct technologies such as AI, IoT, blockchain, and new materials to create a more powerful system for detecting, localizing, and suppressing neural activity, particularly in epilepsy treatment.

Background and Problem Solved

The original patent disclosed a method for detecting, localizing, and suppressing neural activity using acoustic waves and/or ultrasound. However, the method had limitations in terms of detection accuracy, real-time feedback, and secure data storage. The present inventive concept addresses these limitations by incorporating synergistic combinations of technologies to enhance the system's overall performance.

Detailed Description of the Inventive Concept

The enhanced system comprises multiple modules, including a neural activity detection module integrated with an AI-powered seizure prediction algorithm, a real-time feedback mechanism, and an IoT-enabled communication module for transmitting neural activity data to a cloud-based server. Additionally, the system incorporates a novel graphene-based ultrasonic transducer and a blockchain-based system for securely storing and sharing neural activity data. The system also enables synergistic combinations of ultrasound and transcranial magnetic stimulation (TMS) to enhance suppression of neural activity.

Novelty and Inventive Step

The present inventive concept introduces novel combinations of technologies, including AI-powered seizure prediction, IoT-enabled communication, blockchain-based secure data storage, and graphene-based ultrasonic transducers, which provide a significant improvement over the original patent. The inventive step lies in the integration of these distinct technologies to create a more powerful and efficient system for detecting, localizing, and suppressing neural activity.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept may include variations in the AI-powered seizure prediction algorithm, the type of blockchain-based system used, or the materials used for the ultrasonic transducers. Additionally, the system could be integrated with other technologies such as machine learning or computer vision to further enhance its performance.

Potential Commercial Applications and Market

The enhanced system has significant commercial potential in the medical device industry, particularly in the treatment of epilepsy and other neurological disorders. The system's ability to provide real-time feedback and secure data storage makes it an attractive solution for healthcare providers and patients. The market for such a system is substantial, with an estimated value of billions of dollars.

Field of Art

Neurotechnology and medical signal processing, with expertise in non-invasive neural activity detection and suppression techniques, particularly for neurological disorders like epilepsy

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degrees in biomedical engineering, electrical engineering, or neuroscience, possessing knowledge of signal processing, ultrasound technologies, and neural monitoring systems

Obviousness Rationale

A PHOSITA would recognize that integrating additional technologies like AI, IoT, and blockchain with the source patent's ultrasound-based neural activity detection represents predictable combinations of known techniques in the neurological monitoring domain. The fundamental approach of using acoustic waves to detect and suppress neural activity remains consistent, with the PTD merely adding complementary technological enhancements. These variations represent standard engineering approaches to improving existing medical monitoring technologies.

Obvious Combinations & Variations

Source Patent Element
Ultrasound-based neural activity detection method with millimeter-level resolution
PTD Variation
Adding AI-powered seizure prediction algorithm to enhance detection accuracy
Obviousness Reasoning
Integrating machine learning with signal processing is a known technique for improving diagnostic accuracy, representing an obvious enhancement to existing neural monitoring technologies
Source Patent Element
Helmet-integrated ultrasonic transducers for neural activity monitoring
PTD Variation
IoT-enabled communication module for transmitting neural activity data to cloud-based servers
Obviousness Reasoning
Extending medical monitoring devices with networked communication is a predictable technological progression, utilizing standard IoT integration techniques
Source Patent Element
Ultrasound energy in 0.5-1 MHz frequency range for neural activity suppression
PTD Variation
Combining ultrasound with transcranial magnetic stimulation (TMS) for enhanced neural activity suppression
Obviousness Reasoning
Synergistic combination of complementary neural modulation techniques represents an obvious approach for medical practitioners seeking improved intervention strategies
Source Patent Element
Non-invasive neural activity detection method
PTD Variation
Blockchain-based secure data storage and sharing protocol for neural activity information
Obviousness Reasoning
Implementing secure data management techniques is a standard engineering solution for protecting sensitive medical information, representing an obvious technological enhancement
Source Patent Element
Ultrasonic transducer integrated with detection system
PTD Variation
Graphene-based ultrasonic transducer with enhanced signal processing capabilities
Obviousness Reasoning
Exploring advanced materials for sensor construction is a predictable approach for improving device performance, representing a standard engineering design choice
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857811 and the disclosed technological variations, a person having ordinary skill in the art would find the proposed neural activity detection and suppression system variations obvious and lacking inventive step. The combination of ultrasound-based neural monitoring with AI, IoT, blockchain, and advanced materials represents predictable technological extensions that do not rise to the level of non-obvious innovation under 35 U.S.C. Section 103.

Original Patent Information

Patent NumberUS 11,857,811
TitleDetection, localization, and/or suppression of neural activity using acoustic waves and/or ultrasound
Assignee(s)The Board of Trustees of the Leland Stanford Junior University