Advanced High Intensity Focused Ultrasound Systems for Enhanced Tissue Treatment

Publication ID: 24-11857813_0001_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Advanced High Intensity Focused Ultrasound Systems for Enhanced Tissue Treatment,” Published Technical Disclosure No. 24-11857813_0001_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857813_0001_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,813.

Summary of the Inventive Concept

The inventive concept presents significant advancements in high intensity focused ultrasound (HIFU) systems, enabling more effective, efficient, and safe treatment of tissue. By introducing dynamically adjustable ultrasound sources, real-time monitoring, and multi-element transducer arrays, the inventive concept overcomes limitations of existing HIFU systems and expands their therapeutic capabilities.

Background and Problem Solved

The original patent disclosed high intensity focused ultrasound systems for treating tissue, but these systems had limitations in terms of fixed ultrasound frequencies, intensities, and spatial resolution. The inventive concept addresses these limitations by providing more adaptable, precise, and controlled HIFU systems that can be tailored to specific tissue types and treatment objectives.

Detailed Description of the Inventive Concept

The inventive concept comprises four primary components: (1) a dynamically adjustable ultrasound source capable of delivering HIFU waves with varying frequency and intensity; (2) a real-time monitoring module to track tissue response and adjust HIFU wave parameters; (3) a multi-element ultrasound transducer array for improved spatial resolution and precision; and (4) a control module to synchronize transducer elements and optimize treatment. These components enable the inventive concept to selectively disrupt tissue, minimize thermal damage, and optimize treatment duration. The inventive concept also encompasses novel methods for enhancing HIFU treatment efficacy, including applying incremental HIFU pulses and incorporating real-time feedback.

Novelty and Inventive Step

The inventive concept's novelty lies in its integration of dynamically adjustable ultrasound sources, real-time monitoring, and multi-element transducer arrays, which collectively provide unprecedented control and precision in HIFU tissue treatment. The inventive concept's inventive step resides in its ability to overcome the limitations of fixed-frequency and fixed-intensity HIFU systems, thereby expanding the therapeutic capabilities of HIFU technology.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept may include handheld, portable HIFU systems for minimally invasive procedures or larger, more complex systems for treating larger tissue areas. Variations may also involve adapting the inventive concept for specific tissue types, such as cancerous tissue or bleeding spots, or integrating the inventive concept with other therapeutic modalities, such as radiation therapy or chemotherapy.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the medical device industry, particularly in the areas of cancer treatment, cardiovascular disease, and neurology. The inventive concept's ability to provide more effective, efficient, and safe HIFU treatments could lead to widespread adoption in hospitals, clinics, and research institutions, generating substantial revenue and improving patient outcomes.

Field of Art

Medical device technology, specifically high intensity focused ultrasound (HIFU) systems for tissue treatment, requiring advanced knowledge of ultrasound physics, medical imaging, tissue interaction, and biomedical engineering

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device researcher with expertise in ultrasound technology, signal processing, transducer design, and tissue ablation techniques, holding advanced degrees in bioengineering or medical physics

Obviousness Rationale

A person having ordinary skill in the art would recognize that the PTD's disclosed variations represent predictable engineering improvements to the foundational HIFU system disclosed in US 11857813. The proposed dynamic adjustability, real-time monitoring, and multi-element transducer configurations are logical extensions of the source patent's core ultrasound treatment methodology. These variations demonstrate standard problem-solving approaches within HIFU technology development, utilizing known techniques to enhance system performance and precision.

Obvious Combinations & Variations

Source Patent Element
Ultrasound source with a focal region configured to deliver high intensity focused ultrasound to a target tissue site
PTD Variation
Dynamically adjustable ultrasound source capable of delivering HIFU waves with varying frequency and intensity
Obviousness Reasoning
A PHOSITA would recognize frequency and intensity modulation as a predictable design optimization for improving tissue treatment precision, representing a routine engineering enhancement
Source Patent Element
Controller operably coupled to the ultrasound source for delivering HIFU
PTD Variation
Real-time monitoring module to track tissue response and adjust HIFU wave parameters
Obviousness Reasoning
Incorporating feedback mechanisms is a standard control engineering technique for improving system performance, representing an obvious improvement to existing ultrasound treatment controllers
Source Patent Element
HIFU system generating shock waves and cavitation bubbles at the focal region
PTD Variation
Multi-element ultrasound transducer array for improved spatial resolution and precision
Obviousness Reasoning
Utilizing phased array transducer configurations is a known technique for enhancing ultrasound beam focusing and treatment accuracy, representing a predictable technological evolution
Source Patent Element
HIFU pulses with peak positive pressure characteristics
PTD Variation
Applying incremental HIFU pulses with incrementally increasing intensity to minimize thermal damage
Obviousness Reasoning
Pulse modulation strategies are well-understood in ultrasound technology as a method for controlling tissue interaction, representing a routine optimization approach
35 U.S.C. § 103 Summary: Based on the teachings of US 11857813 and the disclosed technical variations, a person having ordinary skill in the art would find the claimed HIFU system improvements obvious and lacking inventive merit. The proposed advancements represent predictable engineering solutions that would be readily conceived by a skilled practitioner seeking to enhance high intensity focused ultrasound treatment methodologies.

Original Patent Information

Patent NumberUS 11,857,813
TitleHigh intensity focused ultrasound systems for treating tissue
Assignee(s)University of Washington