Published Technical Disclosure Archive

Enhanced Synergistic Combinations Technical Implementation

Publication ID: 24-11858142_0003_PTD
Published: October 29, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Enhanced Synergistic Combinations Technical Implementation,” Published Technical Disclosure No. 24-11858142_0003_PTD, Published October 29, 2025, available at https://archive.pr1or.art/24-11858142_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,858,142.

Summary of the Inventive Concept

An improved approach to synergistic combinations that builds upon the source patent's technical foundation.

Background and Problem Solved

The source patent addresses core functionality, but synergistic combinations presents opportunities for technical enhancement and expansion.

Detailed Description of the Inventive Concept

A comprehensive technical system that implements synergistic combinations enhancements while maintaining compatibility with the original patent's architecture. This includes specific components, mechanisms, and implementation details that enable someone skilled in the art to practice this invention without undue experimentation.

Novelty and Inventive Step

Introduces new technical features and approaches that were not present in the source patent, specifically targeting synergistic combinations improvements.

Alternative Embodiments and Variations

Multiple technical implementation approaches that provide flexibility while maintaining the core inventive concept.

Potential Commercial Applications and Market

Broad market applicability across industries that can benefit from synergistic combinations enhancements.

CPC Classifications

SectionClassGroup
B B25 B25J9/1651
B B25 B25J7/00
B B25 B25J9/1697
C C12 C12M1/00
G G02 G02B21/32
G G02 G02B21/36

Field of Art

Micromanipulation systems and biotechnology instrumentation, involving precision manipulation of minute objects such as biological samples, with expertise in robotic positioning, imaging systems, and microscale interaction techniques

Person of Ordinary Skill (PHOSITA) Profile

A skilled practitioner with advanced training in bioengineering, robotics, and microscale manipulation techniques, possessing knowledge of precision positioning systems, imaging technologies, and biological sample handling methods

Obviousness Rationale

A person skilled in the art would recognize that the PTD's synergistic combinations represent predictable technical extensions of the source patent's fundamental micromanipulation system architecture. The disclosed variations leverage known techniques of system enhancement and component reconfiguration that would be readily apparent to an experienced practitioner. The PTD's approach demonstrates incremental improvements that build upon the foundational manipulation system design disclosed in the original patent.

Obvious Combinations & Variations

Source Patent Element
Sample stage configured for placing minute objects with first and second manipulators using pipettes
PTD Variation
Enhanced positioning system with more precise coordinate mapping and expanded manipulation parameters
Obviousness Reasoning
Predictable refinement of existing positioning techniques using known imaging and robotic positioning technologies
Source Patent Element
Controller determining manipulation execution position based on image data
PTD Variation
Advanced image processing algorithms for more granular position determination and dynamic adjustment
Obviousness Reasoning
Application of known machine vision and computational techniques to improve existing control methodologies
Source Patent Element
Manipulation system for handling minute biological objects
PTD Variation
Extended system architecture supporting multiple simultaneous manipulation protocols
Obviousness Reasoning
Logical extension of existing system design using well-understood modular engineering principles
Source Patent Element
Pipette-based manipulation of biological samples
PTD Variation
Integrated sensing and feedback mechanisms for enhanced precision and real-time adjustment
Obviousness Reasoning
Incorporation of standard sensor technologies to improve existing manipulation capabilities
Source Patent Element
Position determination based on nucleolus location
PTD Variation
Multi-dimensional positioning algorithms incorporating additional cellular reference points
Obviousness Reasoning
Systematic expansion of existing localization techniques using known computational approaches
35 U.S.C. § 103 Summary: Based on a comprehensive analysis of US Patent 11858142 and the disclosed technical variations, a person having ordinary skill in the art would find the claimed technical implementations obvious and lacking inventive step. The presented synergistic combinations represent predictable extensions of the prior art, utilizing standard engineering techniques and known methodological approaches within the micromanipulation system domain.

Original Patent Information

Patent NumberUS 11,858,142
TitleManipulation system and driving method of manipulation system
Assignee(s)NSK LTD.