Published Technical Disclosure Archive

Enhanced Synergistic Combinations Technical Implementation

Publication ID: 24-11858142_0008_PTD
Published: October 29, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Enhanced Synergistic Combinations Technical Implementation,” Published Technical Disclosure No. 24-11858142_0008_PTD, Published October 29, 2025, available at https://archive.pr1or.art/24-11858142_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,858,142.

Summary of the Inventive Concept

An improved approach to synergistic combinations that builds upon the source patent's technical foundation.

Background and Problem Solved

The source patent addresses core functionality, but synergistic combinations presents opportunities for technical enhancement and expansion.

Detailed Description of the Inventive Concept

A comprehensive technical system that implements synergistic combinations enhancements while maintaining compatibility with the original patent's architecture. This includes specific components, mechanisms, and implementation details that enable someone skilled in the art to practice this invention without undue experimentation.

Novelty and Inventive Step

Introduces new technical features and approaches that were not present in the source patent, specifically targeting synergistic combinations improvements.

Alternative Embodiments and Variations

Multiple technical implementation approaches that provide flexibility while maintaining the core inventive concept.

Potential Commercial Applications and Market

Broad market applicability across industries that can benefit from synergistic combinations enhancements.

CPC Classifications

SectionClassGroup
B B25 B25J9/1651
B B25 B25J7/00
B B25 B25J9/1697
C C12 C12M1/00
G G02 G02B21/32
G G02 G02B21/36

Field of Art

Biotechnology and precision micromanipulation systems, involving microscopic object handling, imaging-guided manipulation, and robotic positioning for scientific research and cellular procedures

Person of Ordinary Skill (PHOSITA) Profile

A skilled practitioner with expertise in bioengineering, robotics, microscopy, and precision mechanical systems, possessing advanced degrees and practical experience in designing micromanipulation equipment for biological research

Obviousness Rationale

A person skilled in the art would recognize that the PTD's synergistic combinations represent predictable technical extensions of the source patent's fundamental micromanipulation architecture. The disclosed variations leverage known techniques in robotic positioning, imaging-guided manipulation, and component integration that are well-established in precision biotechnology systems. These modifications represent incremental improvements that would be obvious to a skilled practitioner seeking to enhance existing micromanipulation methodologies.

Obvious Combinations & Variations

Source Patent Element
Sample stage for placing minute objects with first and second manipulators using pipettes
PTD Variation
Enhanced stage design with improved positioning mechanisms and integrated imaging alignment features
Obviousness Reasoning
Predictable design optimization using known precision alignment techniques in microscopic manipulation systems
Source Patent Element
Controller determining manipulation positions based on image data
PTD Variation
Advanced image processing algorithms for more precise position determination and automated calibration
Obviousness Reasoning
Known technique of improving computational methods for image-guided robotic positioning
Source Patent Element
Manipulation system with nucleolus-based positioning
PTD Variation
Extended algorithmic approaches for multi-dimensional cellular targeting and dynamic object tracking
Obviousness Reasoning
Finite set of predictable computational extensions for improving cellular manipulation precision
Source Patent Element
Pipette-based minute object manipulation system
PTD Variation
Modular pipette design with enhanced material compatibility and precision control interfaces
Obviousness Reasoning
Routine engineering optimization using known materials science and mechanical design principles
Source Patent Element
Micromanipulation system for biological research applications
PTD Variation
Expanded system architecture supporting multiple simultaneous manipulation protocols
Obviousness Reasoning
Predictable system expansion using known parallel processing and robotic coordination techniques
35 U.S.C. § 103 Summary: Pursuant to 35 U.S.C. ยง 103, the technical variations disclosed herein would have been obvious to a person having ordinary skill in the art at the time of invention, as they represent predictable extensions of the foundational teachings in US Patent 11858142, employing known techniques and design optimizations within the established technological framework of precision micromanipulation systems.

Original Patent Information

Patent NumberUS 11,858,142
TitleManipulation system and driving method of manipulation system
Assignee(s)NSK LTD.